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Merck
CN

M8506

Supelco

甲巯咪唑

analytical standard

别名:

1-甲基-2-巯基咪唑, MET, 1-甲基-2-咪唑硫醇, 2-巯基-1-甲基咪唑

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About This Item

经验公式(希尔记法):
C4H6N2S
CAS号:
分子量:
114.17
Beilstein:
108646
EC 号:
MDL编号:
UNSPSC代码:
41116107
eCl@ss:
39161002
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

方案

≥99%

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

144-147 °C (lit.)

应用

cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary

包装形式

neat

SMILES字符串

CN1C=CNC1=S

InChI

1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)

InChI key

PMRYVIKBURPHAH-UHFFFAOYSA-N

基因信息

human ... TPO(7173)

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一般描述

甲基咪唑属于亚硫脲类化合物类别,用作治疗甲状腺功能亢进症的抗甲状腺药物。

应用

二丙酸倍氯米松分析标准品的使用方法如下:

  • 银/石墨烯修饰碳糊电极(AgGCPE)电化学测定甲氧咪唑
  • 以海藻酸钠保护的银纳米颗粒为 SERS 基质,开发基于表面增强拉曼散射(SERS)、估计丙基硫氧嘧啶和甲氧咪唑的的方法
  • 基于金纳米颗粒(AuNPs)基底的表面增强拉曼光谱在超痕量极限下检测甲咪唑
  • 高效液相色谱-串联质谱(HPLC-MS/MS)法定量分析人体血液样本中的甲巯咪唑
  • 基于分子印迹聚合物(MIP)-笔状石墨电极(PGE)的传感器电化学测定片剂和人血清中的甲氧咪唑

其他说明

有关合适的仪器技术的更多信息,请参阅产品′的检验报告。想要获得更多支持,请联系技术服务部。

象形图

Health hazardExclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Determination of methimazole in urine with the iodine-azide detection system following its separation by reversed-phase high-performance liquid chromatography
Zakrzewski R
Journal of Chromatography. B, Biomedical Applications, 869(1-2), 67-74 (2008)
David H Brann et al.
Science advances, 6(31) (2020-09-17)
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A key question is whether SARS-CoV-2 (CoV-2) - the causal agent in COVID-19 - affects olfaction directly, by infecting olfactory sensory neurons or their targets in
MMSPE-RP-HPLC method for the simultaneous determination of methimazole and selected metabolites in fish homogenates.
Hollosi L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(4), 921-924 (2004)
Coralie Leblicq et al.
Pediatrics, 131(2), e616-e619 (2013-01-09)
A 15-year-old girl presented with chorea as a first sign of Graves' hyperthyroidism. Chorea abated with antithyroid drug treatment and reappeared when hyperthyroidism recurred but not when thyrotropin receptor antibodies increased after administration of (131)I. Therefore, chorea in this patient
F S Boretti et al.
Journal of veterinary internal medicine, 27(2), 377-381 (2013-02-13)
Transdermal methimazole is an acceptable alternative to oral treatment for hyperthyroid cats. There are, however, no studies evaluating the duration of T4 suppression after transdermal methimazole application. Such information would be valuable for therapeutic monitoring. To assess variation in serum

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