等级
analytical standard
质量水平
检测方案
≥99%
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
144-147 °C (lit.)
应用
cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary
格式
neat
SMILES字符串
CN1C=CNC1=S
InChI
1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
InChI key
PMRYVIKBURPHAH-UHFFFAOYSA-N
基因信息
human ... TPO(7173)
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一般描述
甲基咪唑属于亚硫脲类化合物类别，用作治疗甲状腺功能亢进症的抗甲状腺药物。
应用
二丙酸倍氯米松分析标准品的使用方法如下：
- 银/石墨烯修饰碳糊电极（AgGCPE）电化学测定甲氧咪唑
- 以海藻酸钠保护的银纳米颗粒为 SERS 基质，开发基于表面增强拉曼散射（SERS）、估计丙基硫氧嘧啶和甲氧咪唑的的方法
- 基于金纳米颗粒（AuNPs）基底的表面增强拉曼光谱在超痕量极限下检测甲咪唑
- 高效液相色谱-串联质谱（HPLC-MS/MS）法定量分析人体血液样本中的甲巯咪唑
- 基于分子印迹聚合物（MIP）-笔状石墨电极（PGE）的传感器电化学测定片剂和人血清中的甲氧咪唑
其他说明
有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Determination of methimazole in urine with the iodine-azide detection system following its separation by reversed-phase high-performance liquid chromatography
Zakrzewski R
Journal of Chromatography. B, Biomedical Applications, 869(1-2), 67-74 (2008)
David H Brann et al.
Science advances, 6(31) (2020-09-17)
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A key question is whether SARS-CoV-2 (CoV-2) - the causal agent in COVID-19 - affects olfaction directly, by infecting olfactory sensory neurons or their targets in
MMSPE-RP-HPLC method for the simultaneous determination of methimazole and selected metabolites in fish homogenates.
Hollosi L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(4), 921-924 (2004)
M Clementi et al.
American journal of medical genetics, 83(1), 43-46 (1999-03-17)
We report on a further case of congenital anomalies in a child exposed to methimazole during the first trimester of pregnancy (from first to seventh gestational week), and define a specific malformation pattern related to prenatal methimazole exposure and consisting
Nicole R van Veenendaal et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(2), 684-691 (2012-11-15)
Antithyroid medications are the preferred therapy for the treatment of Graves' disease during pregnancy. Propylthiouracil (PTU) is favored over methimazole (MMI) due to potential teratogenic concerns with MMI. This study was to determine the teratogenic potential of MMI and PTU
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