M8506
甲巯咪唑
analytical standard
别名:
1-甲基-2-巯基咪唑, MET, 1-甲基-2-咪唑硫醇, 2-巯基-1-甲基咪唑
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选择尺寸
关于此项目
经验公式（希尔记法）:
C4H6N2S
化学文摘社编号:
分子量:
114.17
NACRES:
NA.24
PubChem Substance ID:
eCl@ss:
39161002
UNSPSC Code:
41116107
EC Number:
200-482-4
MDL number:
Beilstein/REAXYS Number:
108646
产品名称
甲巯咪唑, analytical standard
InChI key
PMRYVIKBURPHAH-UHFFFAOYSA-N
InChI
1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
SMILES string
CN1C=CNC1=S
grade
analytical standard
assay
≥99%
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
144-147 °C (lit.)
application(s)
cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary
format
neat
Quality Level
Gene Information
human ... TPO(7173)
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Application
二丙酸倍氯米松分析标准品的使用方法如下：
- 银/石墨烯修饰碳糊电极（AgGCPE）电化学测定甲氧咪唑
- 以海藻酸钠保护的银纳米颗粒为 SERS 基质，开发基于表面增强拉曼散射（SERS）、估计丙基硫氧嘧啶和甲氧咪唑的的方法
- 基于金纳米颗粒（AuNPs）基底的表面增强拉曼光谱在超痕量极限下检测甲咪唑
- 高效液相色谱-串联质谱（HPLC-MS/MS）法定量分析人体血液样本中的甲巯咪唑
- 基于分子印迹聚合物（MIP）-笔状石墨电极（PGE）的传感器电化学测定片剂和人血清中的甲氧咪唑
General description
甲基咪唑属于亚硫脲类化合物类别，用作治疗甲状腺功能亢进症的抗甲状腺药物。
Other Notes
有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Determination of methimazole in urine with the iodine-azide detection system following its separation by reversed-phase high-performance liquid chromatography
Zakrzewski R
Journal of Chromatography. B, Biomedical Applications, 869(1-2), 67-74 (2008)
MMSPE-RP-HPLC method for the simultaneous determination of methimazole and selected metabolites in fish homogenates.
Hollosi L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 36(4), 921-924 (2004)
David H Brann et al.
Science advances, 6(31) (2020-09-17)
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A key question is whether SARS-CoV-2 (CoV-2) - the causal agent in COVID-19 - affects olfaction directly, by infecting olfactory sensory neurons or their targets in
Coralie Leblicq et al.
Pediatrics, 131(2), e616-e619 (2013-01-09)
A 15-year-old girl presented with chorea as a first sign of Graves' hyperthyroidism. Chorea abated with antithyroid drug treatment and reappeared when hyperthyroidism recurred but not when thyrotropin receptor antibodies increased after administration of (131)I. Therefore, chorea in this patient
F S Boretti et al.
Journal of veterinary internal medicine, 27(2), 377-381 (2013-02-13)
Transdermal methimazole is an acceptable alternative to oral treatment for hyperthyroid cats. There are, however, no studies evaluating the duration of T4 suppression after transdermal methimazole application. Such information would be valuable for therapeutic monitoring. To assess variation in serum
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