所有图片(1)
About This Item
线性分子式:
C7H9N2OCl
CAS号:
分子量:
172.61
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
推荐产品
等级
analytical standard
质量水平
方案
≥97.5%
表单
powder
技术
HPLC: suitable
gas chromatography (GC): suitable
颜色
white
应用
forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products
包装形式
neat
SMILES字符串
[Cl-].C[n+]1cccc(c1)C(N)=O
InChI
1S/C7H8N2O.ClH/c1-9-4-2-3-6(5-9)7(8)10;/h2-5H,1H3,(H-,8,10);1H
InChI key
BWVDQVQUNNBTLK-UHFFFAOYSA-N
一般描述
1-甲基烟酰胺（MNA）是主要由烟酰胺N-甲基转移酶（NNMT）产生的烟酰胺的主要代谢产物，具有抗血栓形成和抗炎作用。
应用
1-甲基烟酰胺氯化物可用作使用离子对反相高效液相色谱法（RP-HPLC）定量尿液样品中1-甲基烟酰胺的标准品。
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生化/生理作用
烟酸代谢的尿排泄产物
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Stefan Chłopicki et al.
Pharmacological reports : PR, 64(2), 369-376 (2012-06-05)
Methylnicotinamide (MNA) displays vasoprotective activity, however, the regulation of the activity of nicotinamide-N-methyltransferase (NNMT), is largely unknown. We analyze a possible involvement of IL-6 in the activation of NNMT-MNA pathway during an endurance exercise. FVB, C57Bl/6J IL6(+/+) and C57Bl/6J IL-6(-/-)
Yoshitaka Tayama et al.
Drug metabolism and pharmacokinetics, 26(1), 94-101 (2010-11-19)
Aldehyde oxidase (AO) plays an important role in metabolizing antitumor and antiviral drugs, including methotrexate, cyclophosphamide and acyclovir. Green tea and its catechins have been shown to modulate the activities of various xenobiotic-metabolizing cytochrome P450 species, both in vivo and
Jacek Miedzobrodzki et al.
Acta poloniae pharmaceutica, 67(5), 487-494 (2010-09-30)
The study was designed to demonstrate the relationship between the activity of human normal monocytes and blood platelets, to determine the metabolic activity of normal monocytes and monocytes cooperating with blood platelets in respect of their generation of reactive oxygen
Quantitation of the niacin metabolites 1-methylnicotinamide and l-methyl-2-pyridone-5-carboxamide in random spot urine samples, by ion-pairing reverse-phase HPLC with UV detection, and the implications for the use of spot urine samples in the assessment of niacin status
Creeke IP, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 817, 247-253 (2005)
Tamara Kuchmerovska et al.
Neurochemistry international, 56(2), 221-228 (2009-10-20)
The present study has been designed to establish the potential benefits from 1-methylnicotinamide (MNA) treatment on brain disorders associated with type 1 diabetes. All experiments were carried out after 6 weeks of streptozotocin-induced diabetes (60 mg/kg of body weight, i.p.)
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