生物来源
plant
质量水平
检测方案
≥98% (GC)
形式
powder
颜色
white
有效pH范围
5.0-6.5 (25 °C, 182 g/L, (77 °F ))
mp
167-170 °C (lit.)
溶解性
water: 100 mg/mL, clear, colorless
储存温度
room temp
SMILES字符串
OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChI key
FBPFZTCFMRRESA-KVTDHHQDSA-N
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一般描述
D-甘露醇是一种天然存在的六碳糖醇或多元醇，存在于藻类、洋葱、草和橄榄等植物中。其血糖指数低于蔗糖，可视为安全。
应用
D-甘露醇已用于：
- 渗透负荷，调节溶液的渗透压
- 用作测试糖溶液的成分，用于纤维二糖-甘露醇渗透性测试
- 用作核磁共振(NMR)内标，比较/分析尿液样本中的甘露醇浓度
- 处理对照细胞并调节高糖渗透压
D-甘露醇已被用作羟基自由基清除剂和介质补充剂。
生化/生理作用
D-甘露醇可以增强AMP活化蛋白激酶(AMPK)和乙酰辅酶A羧化酶1 (ACC) 的磷酸化，可能在脂肪分解和脂肪氧化中具有重要作用。它用作减肥补充剂。D-甘露醇可刺激短链脂肪酸(SCFA)合成，从而调节肝脏中的脂质代谢。
一种糖醇类甜味剂。 用于甜味抑制研究。
WGK
WGK 1
个人防护装备
Eyeshields, Gloves, type N95 (US)
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Journal of clinical microbiology, 33(2), 371-375 (1995-02-01)
Surface-sterilized oocysts of Cryptosporidium parvum were applied to subconfluent monolayers of human adenocarcinoma (HCT-8) cells grown on coverslips in six-well cluster plates. Parasite-infected cultures were then incubated in RPMI 1640 with 10% fetal bovine serum, 15 mM HEPES (N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid)
A Matsuzaki et al.
Cancer research, 49(20), 5702-5707 (1989-10-15)
Rat 3Y1 fibroblasts transformed by the E1A gene of adenovirus type 12 (E1A-3Y1 cells) are highly sensitive to the cell-killing effect of 1,3-dilinoleoylglycerol (DLG) administered in a culture medium, whereas the parental 3Y1 cells are less sensitive (H. Shimura et
Heikki O Koskela et al.
Chest, 125(6), 1985-1992 (2004-06-11)
To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma. A prospective study. University hospital. Thirty-seven steroid-naive, asthmatic subjects and 10 healthy subjects. The participants completed a symptom questionnaire, recorded
Diana Bilton et al.
Thorax, 69(12), 1073-1079 (2014-09-24)
Bronchiectasis is characterised by excessive production of mucus and pulmonary exacerbations. Inhaled osmotic agents may enhance mucociliary clearance, but few long-term clinical trials have been conducted. To determine the impact of inhaled mannitol on exacerbation rates in patients with non-cystic
Marieke Dubois et al.
Plant physiology, 169(1), 166-179 (2015-05-23)
Leaf growth is a tightly regulated and complex process, which responds in a dynamic manner to changing environmental conditions, but the mechanisms that reduce growth under adverse conditions are rather poorly understood. We previously identified a growth inhibitory pathway regulating
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