推荐产品
等级
analytical standard
质量水平
表单
crystalline
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
159-161 °C (lit.)
抗生素抗菌谱
Gram-negative bacteria
parasites
应用
forensics and toxicology
pharmaceutical (small molecule)
包装形式
neat
作用机制
DNA synthesis | interferes
储存温度
2-8°C
SMILES字符串
CC1=NC=C([N+]([O-])=O)N1CCO
InChI
1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3
InChI key
VAOCPAMSLUNLGC-UHFFFAOYSA-N
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一般描述
甲硝唑（Metronidazole）是一种硝基咪唑类药物，尤其适合用于治疗由厌氧菌和原生动物引起的人类和家畜感染。
应用
此分析标准品可用于以下用途：
- 碳糊电极 (CPE) 循环伏安法测定三种不同品牌甲硝唑片中甲硝唑的含量
- 采用反相高效液相色谱-光电二极管阵列检测器（RP- HPLC-DAD)同时测定制药剂量的甲硝唑、二氯尼特、螺旋霉素和克利喹诺
- 开发基于聚多巴胺/羧基多壁碳纳米管(MWCNTs-COOH)纳米复合材料的电化学传感器，测定甲硝唑
- 液相色谱–离子阱质谱法(LC-MS/MS法分析在水、沉积物和鱼组织样本中的甲硝唑）
- 基于多壁碳纳米管 (MWCNT) 和壳聚糖-镍络合物 (CTS-Ni) 的电化学传感器测定片剂、人尿液和血清样品中的甲硝唑
其他说明
有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
警示用语：
Danger
危险声明
危险分类
Carc. 1B - Muta. 1B - STOT RE 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Alison L Huckenpahler et al.
Translational vision science & technology, 9(10), 18-18 (2020-09-29)
To observe and characterize cone degeneration and regeneration in a selective metronidazole-mediated ablation model of ultraviolet-sensitive (UV) cones in zebrafish using in vivo optical coherence tomography (OCT) imaging. Twenty-six sws1:nfsB-mCherry;sws2:eGFP zebrafish were imaged with OCT, treated with metronidazole to selectively
Samrah Masud et al.
Autophagy, 15(5), 796-812 (2019-01-25)
Innate immune defense against intracellular pathogens, like Salmonella, relies heavily on the autophagy machinery of the host. This response is studied intensively in epithelial cells, the target of Salmonella during gastrointestinal infections. However, little is known of the role that
Marcos Sande-Melón et al.
Cell reports, 29(4), 1041-1054 (2019-10-24)
During heart regeneration in the zebrafish, fibrotic tissue is replaced by newly formed cardiomyocytes derived from preexisting ones. It is unclear whether the heart is composed of several cardiomyocyte populations bearing different capacity to replace lost myocardium. Here, using sox10
Christina M Surawicz et al.
The American journal of gastroenterology, 108(4), 478-498 (2013-02-27)
Clostridium difficile infection (CDI) is a leading cause of hospital-associated gastrointestinal illness and places a high burden on our health-care system. Patients with CDI typically have extended lengths-of-stay in hospitals, and CDI is a frequent cause of large hospital outbreaks
T H I Brummer et al.
BJOG : an international journal of obstetrics and gynaecology, 120(10), 1269-1276 (2013-06-22)
To evaluate cefuroxime and metronidazole antibiotic prophylaxis. Observational nonrandomised 1-year prospective cohort study. Fifty-three hospitals in Finland. A total of 5279 women undergoing hysterectomy for benign indications, with cefuroxime given to 4301 and metronidazole given to 2855. Excluding other antibiotics
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