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产品名称
黑色素 来源于墨鱼, 99% (TLC)
质量水平
方案
99% (TLC)
表单
powder
溶解性
hydrogen peroxide: 1 mg/mL, dark brown
应用
diagnostic assay manufacturing
hematology
histology
储存温度
−20°C
SMILES字符串
[nH]1c2c3c(c4c5c([nH]c4)c([c]([c](c5c3c1)=O)=O)C)[c]([c](c2C)=O)=O
InChI
1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3
InChI key
XUMBMVFBXHLACL-UHFFFAOYSA-N
一般描述
黑色素是普遍存在的重要色素，影响皮肤、头发和眼睛颜色。黑色素分为真黑色素和褐黑色素（pheomelanin）。真黑色素是黑色至深棕色的色素，存在于黑发和眼部视网膜。褐黑色素为黄色至红棕色的色素，存在于红发和红色羽毛。黑色素是高分子量色素，由酚或吲哚前体合成，广泛存在于动物、植物和微生物中。
应用
乌贼（ Sepia officinalis ）来源黑色素可用作：
- 天然色素，测量拉曼（Raman）光谱
- 在竞争性酶联免疫吸附测定（ELISA）中，鉴定噬菌体抗体
- 作为外部标准品，用分光光度法检测 B16F10 细胞生成黑色素的情况
生化/生理作用
黑色素能清除活性化学物质，用作防晒霜。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Chikako Yoshikawa-Murakami et al.
International journal of molecular sciences, 21(22) (2020-11-18)
Melanin incorporated into keratinocytes plays an important role in photoprotection; however, abnormal melanin accumulation causes hyperpigmentary disorders. To understand the mechanism behind the accumulation of excess melanin in the skin, it is essential to clarify the spatial distribution of melanosomes
Detection of antibodies against Paracoccidioides brasiliensis melanin in in vitro and in vivo studies during infection.
Uran ME
Clinical and Vaccine Immunology : CVI, 18, 1680-1680 (2011)
Sunil Kalia et al.
Pigment cell & melanoma research, 31(1), 31-38 (2017-08-15)
Objective measurements of melanin can provide important information for differentiating melanoma from benign pigmented lesions and in assessing pigmentary diseases. Herein, we evaluate near-infrared (NIR) fluorescence as a possible tool to quantify melanin. Various concentrations of in vitro Sepia melanin
Bor-Kai Hsiung et al.
The Journal of experimental biology, 218(Pt 22), 3632-3635 (2015-10-10)
Melanin pigments are broadly distributed in nature - from bacteria to fungi to plants and animals. However, many previous attempts to identify melanins in spiders were unsuccessful, suggesting that these otherwise ubiquitous pigments were lost during spider evolution. Yet, spiders
Influence of rosmarinic acid and Salvia officinalis extracts on melanogenesis of B16F10 cells
Oliveira KB, et al.
Revista Brasileira de Farmacognosia, 23(2), 249-258 (2013)
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