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Merck
CN

M1808000

Metixene hydrochloride

European Pharmacopoeia (EP) Reference Standard

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别名:
Methixene monohydrochloride monohydrate
经验公式(希尔记法):
C20H23NSl · HCl · H2O
CAS号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

metixene

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

InChI

1S/C20H23NS.ClH.H2O/c1-21-12-6-7-15(14-21)13-18-16-8-2-4-10-19(16)22-20-11-5-3-9-17(18)20;;/h2-5,8-11,15,18H,6-7,12-14H2,1H3;1H;1H2

InChI key

RAOHHYUBMJLHNC-UHFFFAOYSA-N

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Metixene hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

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M I Walash et al.
Pharmaceutisch weekblad. Scientific edition, 8(4), 234-238 (1986-08-22)
A simple and rapid colorimetric method for the quantitative determination of the thioxanthene derivatives, chlorprothixene, tiotixene and metixene has been performed either in their pure form or in tablets. The procedure is based upon the formation of charge transfer complexes
JAMA, 195(10), 851-851 (1966-03-07)
Methixene hydrochloride, an anticholinergic agent, may be useful in the symptomatic treatment of functional bowel disorders. Adverse effects reported from its use are those of the anticholinergic drugs in general.
[An anticholinergic agent, the side effect of mouth dryness and hazards for the teeth].
W H van Palenstein Helderman et al.
Nederlands tijdschrift voor geneeskunde, 127(51), 2318-2321 (1983-12-17)
P A Fischer et al.
Journal of neural transmission. Supplementum, 25, 137-147 (1987-01-01)
To quantify the clinical benefit of an additional deprenyl administration in L-dopa pretreated patients we have performed a study of 30 patients suffering from advanced parkinsonism. During the first phase of the study over three months under controlled conditions deprenyl
S L Levin
International journal of clinical pharmacology research, 6(5), 429-439 (1986-01-01)
Dualism in the effects of atropine, and metixene upon the denervated human parotid salivary gland is demonstrated by the fact that they suppress pilocarpine secretion while themselves causing an extremely intense and prolonged salivation. A still stronger cholinolytic, chlorosyle, although

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