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Merck
CN

M0215000

甲苯咪唑

European Pharmacopoeia (EP) Reference Standard

别名:

5-苯甲酰-2-苯并咪唑胺甲酸甲酯, 甲基N-(5-苯甲酰基-1H-苯并咪唑-2-基)氨基甲酸酯, 甲苯咪唑

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About This Item

经验公式(希尔记法):
C16H13N3O3
CAS号:
分子量:
295.29
Beilstein:
759809
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

mebendazole

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3

InChI

1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)

InChI key

OPXLLQIJSORQAM-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Mebendazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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分析证书(COA)

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R W Ammann et al.
Journal of hepatology, 29(6), 994-998 (1999-01-06)
Long-term chemotherapy of human alveolar echinococcosis with benzimidazole compounds (mebendazole, albendazole) has been shown to be primarily parasitostatic, but its curative (parasitocidal) efficacy is debated. This article reports on a 67-year-old male patient with non-resectable alveolar echinococcosis of the liver
Cong-Shan Liu et al.
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 27(6), 513-519 (2010-03-18)
Mebendazole is currently used in the treatment of hydatid disease. Its poor absorption from the gastrointestinal tract and low bioavailability aroused further research on new formulations of mebendazole to increase the bioavailability and improve the therapeutic efficacy. This review summarizes
A Bennett et al.
Parasitology today (Personal ed.), 16(2), 71-74 (2000-02-01)
The widespread use of mebendazole and albendazole for treating intestinal nematode infections in human populations is raising concerns that careful monitoring pro- cedures should be in place to identify any emergence of drug resistance. In this article, Andy Bennett and
Olga Staudacher et al.
Tropical medicine & international health : TM & IH, 19(7), 812-824 (2014-04-23)
Preventive chemotherapy of schoolchildren against soil-transmitted helminths (STHs) is widely implemented in Rwanda. However, data on its actual efficacy are lacking. We assessed prevalence, associated factors and manifestation of STH infection among schoolchildren in southern highland Rwanda as well as
Mebendazole and related anthelmintics.
H Van den Bossche et al.
Advances in pharmacology and chemotherapy, 19, 67-128 (1982-01-01)

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