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Merck
CN

LIGHTOX23

Sigma-Aldrich

LightOx23

≥95% (HPLC)

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经验公式(希尔记法):
C21H25NO2
分子量:
323.43
UNSPSC代码:
12352200
NACRES:
NA.22

检测方案

≥95% (HPLC)

形式

powder

储存温度

2-8°C

应用

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

生化/生理作用

Weak ligand for retinoic acid receptor proteins

特点和优势

LightOx23 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a weak ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx23 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

其他说明

Chemical Equivalency 1ea=1mg

法律信息

LightOx is a trademark of LightOx Ltd.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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商品

Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.

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