InChI key
HVYWMOMLDIMFJA-DPAQBDIFSA-N
InChI
1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
SMILES string
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
biological source
synthetic
assay
≥98% (GC)
form
powder
packaging
pkg of 1 × 1 g IA00001-1G
color
white to off-white
bp
360 °C (lit.)
mp
147-149 °C (lit.), 147-150
solubility
ethanol: soluble, soluble
density
1.067 g/mL at 25 °C (lit.)
shipped in
dry ice
storage temp.
−20°C
Quality Level
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General description
Synthetic cholesterol has various applications in pharmaceutical research, including:
1.Drug Development: Cholesterol analogs are used in the development of drugs targeting cholesterol metabolism and related diseases such as atherosclerosis.
2.Biological Studies: Synthetic cholesterol is utilized to study the effects of cholesterol on cells, cellular processes, and as a standard in biological experiments.
3.Vaccine Development: It is used in the formulation of lipid-based adjuvants for vaccine development due to its ability to enhance immune responses.
4.Drug Delivery System Research: Cholesterol derivatives are incorporated into drug delivery systems to enhance the stability and bioavailability of pharmaceutical compounds.
5.Membrane Studies: Synthetic cholesterol is used to mimic the properties of cell membranes, aiding in the study of drug interactions and membrane permeability.
6.Disease Modeling: It is employed in disease modeling and in vitro studies to understand the role of cholesterol in various diseases.
1.Drug Development: Cholesterol analogs are used in the development of drugs targeting cholesterol metabolism and related diseases such as atherosclerosis.
2.Biological Studies: Synthetic cholesterol is utilized to study the effects of cholesterol on cells, cellular processes, and as a standard in biological experiments.
3.Vaccine Development: It is used in the formulation of lipid-based adjuvants for vaccine development due to its ability to enhance immune responses.
4.Drug Delivery System Research: Cholesterol derivatives are incorporated into drug delivery systems to enhance the stability and bioavailability of pharmaceutical compounds.
5.Membrane Studies: Synthetic cholesterol is used to mimic the properties of cell membranes, aiding in the study of drug interactions and membrane permeability.
6.Disease Modeling: It is employed in disease modeling and in vitro studies to understand the role of cholesterol in various diseases.
Application
Advanced drug delivery
Biochem/physiol Actions
所有生物膜的主要成分；总脑脂质中约25%为胆固醇。
Features and Benefits
Research grade products that can easily be scaled to meets GMP needs.
Legal Information
SyntheChol is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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