推荐产品
应用
碘乙酸用作：烷基化剂，适用抗体AR37、 血清蛋白、 和从成熟果实不同阶段提取的草莓蛋白质组样品。
蛋白质中半胱氨酸残基的改性剂。
生化/生理作用
碘乙酸（IAA）封闭半胱氨酸的巯基。通过与半胱氨酸活性位点的巯基相互作用，IAA抑制3-磷酸甘油醛脱氢酶（G3PDH）。IAA 抑制实体艾氏（Ehrlich）癌的进展。IAA 是饮用水进行碘化消毒的一种副产物。对哺乳动物细胞存在细胞毒性。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1A
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
Drinking water disinfection byproduct iodoacetic acid induces tumorigenic transformation of NIH3T3 cells
Wei X, et al.
Environmental Science & Technology, 47(11), 5913-5920 (2013)
Quantitative proteomic investigation employing stable isotope labeling by peptide dimethylation on proteins of strawberry fruit at different ripening stages
Li L, et al.
Journal of Proteomics, 94(5), 219-239 (2013)
Antitumor activities of iodoacetate and dimethylsulphoxide against solid Ehrlich carcinoma growth in mice
Fahim FA, et al.
Biological Research, 36(2), 253-262 (2003)
Development of candidate biomarkers for pancreatic ductal adenocarcinoma using multiple reaction monitoring
Yu J, et al.
Biotechnology and Bioprocess Engineering: BBE, 18(5), 1038-1047 (2013)
Database-independent Protein Sequencing (DiPS) Enables Full-length de Novo Protein and Antibody Sequence Determination
Savidor A, et al.
Molecular and Cellular Proteomics, 16(6), 1151-1161 (2017)
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