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主要文件

I0375000

Isoconazole

European Pharmacopoeia (EP) Reference Standard

别名:

1-[2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole

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About This Item

经验公式(希尔记法):
C18H14Cl4N2O
CAS号:
分子量:
416.13
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

isoconazole

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

Clc1c(c(ccc1)Cl)COC(C[n]3cncc3)c2c(cc(cc2)Cl)Cl

InChI

1S/C18H14Cl4N2O/c19-12-4-5-13(17(22)8-12)18(9-24-7-6-23-11-24)25-10-14-15(20)2-1-3-16(14)21/h1-8,11,18H,9-10H2

InChI key

MPIPASJGOJYODL-UHFFFAOYSA-N

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Isoconazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

相关产品

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

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J Lademann et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 80(3), 615-620 (2012-01-31)
Bacteria and fungi are located in the stratum corneum and the hair follicles. Therefore, the development and assessment of efficient drugs requires standard in vivo investigation methods permitting a differentiation between intercellular and follicular penetration and storage of topically applied
Marcus Henrique de S B Xavier et al.
Dermatology online journal, 14(8), 15-15 (2008-12-09)
Tinea nigra is an asymptomatic superficial fungal infection caused by Phaeoannelomyces werneckii, generally affecting the skin of the palms and characterized by deeply pigmented macular non-scaly patches. These lesions are quite characteristic. However, they can be misdiagnosed as a malignant
Tinea cruris treated with a combined topical therapy containing isoconazole and a corticosteroid.
Jaco Jürgens
Mycoses, 51 Suppl 4, 32-33 (2008-09-12)
Tinea corporis of the shin and chest successfully treated with a topical antifungal and corticosteroid cream.
Ga-Young Lee et al.
Mycoses, 51 Suppl 4, 34-36 (2008-09-12)
Irina Vennewald et al.
Clinics in dermatology, 28(2), 202-211 (2010-03-30)
Aspergillus and Candida spp are the most frequently isolated fungi in patients with otomycosis. The diagnosis of otitis externa relies on the patient's history, otoscopic examination under microscopic control, and imaging studies. Direct preparation of the specimens, particularly with optical

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