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Merck
CN

H9645

Supelco

对羟基甲基苯丙胺

analytical standard, for drug analysis

别名:

Pholderin

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About This Item

经验公式(希尔记法):
C10H15NO
CAS号:
分子量:
165.23
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard, for drug analysis

质量水平

方案

≥98% (TLC)

drug control

Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

包装形式

neat

储存温度

−20°C

SMILES字符串

CNC(C)Cc1ccc(O)cc1

InChI

1S/C10H15NO/c1-8(11-2)7-9-3-5-10(12)6-4-9/h3-6,8,11-12H,7H2,1-2H3

InChI key

SBUQZKJEOOQSBV-UHFFFAOYSA-N

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应用

有关合适的仪器技术的更多信息,请参阅产品′检验报告。想要获得更多支持,请联系技术服务部。

生化/生理作用

甲基苯丙胺的代谢物;拟交感神经药

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Shimosato, K., et al.
Journal of Chromatographic Science, 377, 279-279 (1986)
H Wilhelm et al.
Klinische Monatsblatter fur Augenheilkunde, 204(3), 169-175 (1994-03-01)
Pharmacologic testing by indirect acting sympathomimetics like hydroxyamphetamine may determine the site of the lesion in Horner's syndrome. Pholedrine is chemically similar to hydroxyamphetamine. Therefore we examined if it shows the same effects in normal subjects and in patients with
A Hutchaleelaha et al.
Biopharmaceutics & drug disposition, 18(5), 423-432 (1997-07-01)
p-hydroxymethamphetamine (OHMAP) is one of the major metabolites of the widely abused drug methamphetamine (MAP). The demethylation of OHMAP to p-hydroxyamphetamine (OHAP) has been shown in vitro but has never been reported in vivo. The disposition kinetics as well as
K Hara et al.
Journal of analytical toxicology, 21(1), 54-58 (1997-01-01)
A simple, extractive heptafluoro-n-butyrylation with Extrelut columns was devised to simultaneously measure methamphetamine (MAMP), amphetamine (AMP), 4-hydroxymethamphetamine (HMAMP), and 4-hydroxyamphetamine (HAMP) in biological materials by gas chromatography-mass spectrometry (GC-MS) using 4-methoxymethamphetamine-d5 as the internal standard. Human urine, human whole blood
A T Bates et al.
Journal of neurology, neurosurgery, and psychiatry, 58(2), 215-217 (1995-02-01)
Mydriatic responses to eyedrops containing the indirect acting sympathomimetic amines tyramine, hydroxyamphetamine, and pholedrine have been compared in 10 healthy subjects. Pholedrine, the n-methyl derivative of hydroxyamphetamine, at a concentration of 1% had effects similar to those produced by 0.5%

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