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Merck
CN

H4125

检皮素

analytical standard

别名:

3′,5,7-三羟基-4′-甲氧基黄酮, 5,7-二羟基-2-(3-羟基-4-甲氧基苯基)-4-苯并二氢吡喃-4-酮

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关于此项目

经验公式(希尔记法):
C16H14O6
化学文摘社编号:
分子量:
302.28
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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产品名称

检皮素, analytical standard

InChI

1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3

SMILES string

COc1ccc(cc1O)C2CC(=O)c3c(O)cc(O)cc3O2

InChI key

AIONOLUJZLIMTK-UHFFFAOYSA-N

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

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Application

有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务部门。
使用酶联免疫吸附试验 (ELISA) 技术,在涉及橙皮素对阿霉素耐药 MCF-7 细胞的细胞毒性作用的研究中,橙皮素已被用作标准品。

Biochem/physiol Actions

具有化学预防作用的膳食黄烷酮。

General description

橙皮素是一种苷元形式的类黄酮,人们还在柑桔果皮中发现这种物质。

Other Notes

此产品我们采用非立体特异性的CAS号。虽然该物质主要由天然对映体构成,但它在溶液中很容易发生消旋作用。因此该产品并不能保证一定是立体特异性的,建议只将其用于非立体特异性分析。

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Increasing sensitivity of MCF-7/DOX cells towards doxorubicin by hesperetin through suppression of P-glycoprotein expression
Sarmoko, et al.
Indonesian Journal of Pharmacy, 25, 84-84 (2014)
Manoj Aswar et al.
Pharmacology, biochemistry, and behavior, 124, 101-107 (2014-05-30)
Behavioral, biochemical and gene expression changes were investigated in a rat model of partial sciatic nerve ligation (PSNL) after administration of hesperetin (20, 50mg/kg; p.o.), pregabalin (10mg/kg; p.o.) or vehicle (1 ml/kg, p.o.). Thirty-six animals were randomly divided into six
Benjamin Dilberger et al.
Nutrients, 11(8) (2019-08-16)
(1) Background: Polyphenols (PP) play an important role in the prevention of non-communicable diseases and may contribute to healthy aging. To investigate the molecular and cellular aspects of PP metabolites on longevity with a focus on mitochondrial function, we applied
Fei Ding et al.
Molecular bioSystems, 11(4), 1119-1133 (2015-02-13)
Naturally multifunctional Rutaceae hesperidin and its aglycone hesperetin have a great variety of biopharmaceutical activities, e.g. anti-cancer, anti-inflammatory, antioxidant and antitumor; however, the influence of the molecular structures of hesperidin and hesperetin, and in particular, the structural properties such as
Jixiang Zhang et al.
Medical oncology (Northwood, London, England), 32(4), 101-101 (2015-03-05)
Hesperetin, a flavonoid from citrus fruits, has been proved to possess biological activity on various types of human cancers. However, few related studies on hepatocellular carcinoma are available. In this study, we aimed to investigate the effect of hesperetin on

商品

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。

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