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Merck
CN

H4125

Supelco

检皮素

analytical standard

别名:

3′,5,7-三羟基-4′-甲氧基黄酮, 5,7-二羟基-2-(3-羟基-4-甲氧基苯基)-4-苯并二氢吡喃-4-酮

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About This Item

经验公式(希尔记法):
C16H14O6
CAS号:
分子量:
302.28
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

food and beverages

格式

neat

储存温度

2-8°C

SMILES字符串

COc1ccc(cc1O)C2CC(=O)c3c(O)cc(O)cc3O2

InChI

1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3

InChI key

AIONOLUJZLIMTK-UHFFFAOYSA-N

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一般描述

橙皮素是一种苷元形式的类黄酮,人们还在柑桔果皮中发现这种物质。

应用

使用酶联免疫吸附试验 (ELISA) 技术,在涉及橙皮素对阿霉素耐药 MCF-7 细胞的细胞毒性作用的研究中,橙皮素已被用作标准品。
有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务部门。

生化/生理作用

具有化学预防作用的膳食黄烷酮。

其他说明

此产品我们采用非立体特异性的CAS号。虽然该物质主要由天然对映体构成,但它在溶液中很容易发生消旋作用。因此该产品并不能保证一定是立体特异性的,建议只将其用于非立体特异性分析。

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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Increasing sensitivity of MCF-7/DOX cells towards doxorubicin by hesperetin through suppression of P-glycoprotein expression
Sarmoko, et al.
Indonesian Journal of Pharmacy, 25, 84-84 (2014)
Manoj Aswar et al.
Pharmacology, biochemistry, and behavior, 124, 101-107 (2014-05-30)
Behavioral, biochemical and gene expression changes were investigated in a rat model of partial sciatic nerve ligation (PSNL) after administration of hesperetin (20, 50mg/kg; p.o.), pregabalin (10mg/kg; p.o.) or vehicle (1 ml/kg, p.o.). Thirty-six animals were randomly divided into six
Benjamin Dilberger et al.
Nutrients, 11(8) (2019-08-16)
(1) Background: Polyphenols (PP) play an important role in the prevention of non-communicable diseases and may contribute to healthy aging. To investigate the molecular and cellular aspects of PP metabolites on longevity with a focus on mitochondrial function, we applied
Jixiang Zhang et al.
Medical oncology (Northwood, London, England), 32(4), 101-101 (2015-03-05)
Hesperetin, a flavonoid from citrus fruits, has been proved to possess biological activity on various types of human cancers. However, few related studies on hepatocellular carcinoma are available. In this study, we aimed to investigate the effect of hesperetin on
Mari Nekohashi et al.
PloS one, 9(5), e97901-e97901 (2014-05-27)
Niemann-Pick C1-Like 1 (NPC1L1) mediates cholesterol absorption, and ezetimibe is a potent NPC1L1 inhibitor applicable for medication of hypercholesterolemia. Epidemiological studies demonstrated that consumption of polyphenols correlates with a decreased risk for atherosclerosis due to their antioxidant effect. This activity

商品

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。

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