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Merck
CN

G6639

Sigma-Aldrich

异硫氰酸胍

≥97% (titration)

别名:

硫氰酸亚脲, 硫氰酸胍

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About This Item

线性分子式:
NH2C(=NH)NH2 · HSCN
CAS号:
分子量:
118.16
Beilstein:
3563461
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.55

生物来源

synthetic

质量水平

方案

≥97% (titration)

表单

powder or crystals

技术

RNA extraction: suitable

颜色

white to off-white

mp

120-122 °C (lit.)

溶解性

water: 4 M, clear, colorless

痕量阴离子

chloride (Cl-): ≤2.5%

SMILES字符串

SC#N.NC(N)=N

InChI

1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H

InChI key

ZJYYHGLJYGJLLN-UHFFFAOYSA-N

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应用

硫氰酸胍可用于:
  • 用作变性剂研究其对球状蛋白表面活性的影响
  • 从原代肝细胞提取总核糖核酸(RNA)
  • 用作从人骨中提取DNA的培养缓冲液组分
  • 用作提取象鼻鲨的DNA的硫氰酸胍(GITC)裂解缓冲液组分
  • 用作从大鼠胰腺组织提取RNA的裂解液组分
离液剂和强效变性剂;溶解细胞。

生化/生理作用

硫氰酸胍(GTC)是一种强效蛋白质变性剂,能够变性内源性核糖核酸酶。它在从核糖体中分离核蛋白体核糖核酸(rRNA)方面起着重要作用。GTC可与苯酚、氯仿联用,从细胞和组织中分离总核糖核酸。

象形图

CorrosionExclamation mark

警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C

补充剂危害

储存分类代码

8B - Non-combustible corrosive hazardous materials

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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