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Merck
CN

G5882

戊二醛 溶液

Grade I, 25% in H2O, specially purified for use as an electron microscopy fixative

别名:

1,5-戊二醛, 五碳双缩醛 溶液

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线性分子式:
OHC(CH2)3CHO
化学文摘社编号:
111-30-8
分子量:
100.12
UNSPSC Code:
12352114
NACRES:
NA.21
PubChem Substance ID:
24895235
MDL number:
MFCD00007025
Beilstein/REAXYS Number:
605390

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产品名称

戊二醛 溶液, Grade I, 25% in H2O, specially purified for use as an electron microscopy fixative

InChI

1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2

SMILES string

[H]C(CCCC([H])=O)=O

InChI key

SXRSQZLOMIGNAQ-UHFFFAOYSA-N

type

Grade I

form

liquid

concentration

25% in H2O

technique(s)

electron microscopy: suitable (fixative)
electron microscopy: suitable

color

colorless

useful pH range

2.9

mp

-10 °C ((14 °F ))

solubility

water: soluble at 20 °C

application(s)

cell analysis

shipped in

dry ice

storage temp.

−20°C

Quality Level

300

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相关类别

Application

戊二醛溶液已用于：
  • 固定血液样品，进行扫描电镜(SEM)观察
  • 固定支架进行SEM分析
  • 在药物实验中处理K562（白血病）细胞，永久交联细胞组分

Biochem/physiol Actions

戊二醛在生物医学研究中可用来固定细胞。还可作为健康和病理红细胞的研究工具。戊二醛广泛用于消毒各种医疗器械，包括内窥镜、透析管、血液透析比例混合和透析液供给系统、腔内探头、换能器、麻醉、呼吸治疗设备以及一次性腹腔镜塑料套管的再利用。

Features and Benefits

  • 功能强大，适用于各种研究应用
  • 即用型溶液减少制备时间

General description

戊二醛（1,5-戊二醛）是一种脂肪族二醛，常用作多功能生物化学试剂。戊二醛溶液由固定性能不同的单体和聚合体混合而成。其应用包括作为蛋白质交联剂，促进显微镜学、组织化学和细胞化学中酶的固定。该化合物可用作SDS-PAGE、染色或电子显微镜检查之前的胺反应性同型双功能交联剂和细胞固定剂，适用于各种形态学研究。
戊二醛可以使胺和肼衍生物与蛋白质和其它含胺聚合物高效交联。特别值得一提的是，它已被用于某些反应中，使生物素酰肼与核酸直接结合，其潜在应用为荧光酰肼和羟胺与DNA的偶联。在组织学研究中，戊二醛可用于保存组织切片，以便进行更密切的检查。

Other Notes

2024年CiteAb奖——成功的帕金森研究供应商(2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research)
为了全面了解我们针对客户研究提供的各种单糖产品，建议您访问我们的碳水化合物分类页面。
如需了解生化试剂系列的更多信息，请填写此表。
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signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000512615
0000512615
0000506481
0000506481
0000502259

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The side effects induced by nanoparticle exposure at a cellular level are one of the priority research topics due to the steady increase in the use of nanoparticles (NPs). Recently, the focus on cellular morphology and mechanical behavior is gaining
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Patients with severe malaria treated with artesunate sometimes experience a delayed hemolytic episode. Artesunate (AS) induces pitting, a splenic process whereby dead parasites are expelled from their host erythrocytes. These once-infected erythrocytes then return to the circulation. We analyzed hematologic
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