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等级
analytical standard
质量水平
检测方案
≥97.5% (HPLC)
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
267-269 °C (lit.)
应用
forensics and toxicology
veterinary
格式
neat
SMILES字符串
CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
InChI
1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1
InChI key
FEBLZLNTKCEFIT-VSXGLTOVSA-N
基因信息
human ... NR3C1(2908)
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应用
Fluocinolone acetonide may be used as a reference standard in the analysis of fluocinolone acetonide in samples of soil via pressurized liquid extraction (PLE) and solid-phase extraction (SPE) followed by liquid chromatography coupled with tandem mass spectrometry (LC/MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
监管及禁止进口产品
Analytical method for the determination of trace levels of steroid hormones and corticosteroids in soil, based on PLE/SPE/LC-MS/MS.
Gineys N, et al.
Analytical and Bioanalytical Chemistry, 397(6), 2295-2302 (2010)
Peter A Campochiaro et al.
Ophthalmology, 119(10), 2125-2132 (2012-06-26)
To assess long-term efficacy and safety of intravitreal inserts releasing 0.2 μg/d (low dose) or 0.5 μg/d (high dose) fluocinolone acetonide (FAc) in patients with diabetic macular edema (DME). Two randomized, sham injection-controlled, double-masked, multicenter clinical trials. Subjects with persistent
Benjamin P Nicholson et al.
American journal of ophthalmology, 154(6), 969-973 (2012-09-18)
To characterize the phenomenon of dissociation of the 2 components of the sustained-release fluocinolone acetonide implant (Retisert; Bausch & Lomb) during removal or exchange procedures, or both, and to evaluate outcomes after these events. Retrospective, observational case series. Retrospective review
Raymond Iezzi et al.
Biomaterials, 33(3), 979-988 (2011-11-04)
Retinal neuroinflammation, mediated by activated microglia, plays a key role in the pathogenesis of photoreceptor and retinal pigment epithelial cell loss in age-related macular degeneration and retinitis pigmentosa. Targeted drug therapy for attenuation of neuroinflammation in the retina was explored
Oliver Comyn et al.
Current opinion in ophthalmology, 24(3), 248-254 (2013-03-23)
Three long-acting corticosteroid implants are now available for the treatment of retinal disease, offering control of macular edema and inflammation for between 6 months and up to 3 years. This review evaluates their efficacy and side-effect profile in comparison with
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