推荐产品
产品名称
荧光素 钠盐, used as fluorescent tracer
质量水平
表单
powder
技术
titration: suitable
颜色
orange to brown
pH值(酸碱度)
8.3 (20 °C, 10 g/L)
mp
>300 °C
溶解性
H2O: 1 mg/mL
密度
0.78 g/cm3 at 29.6 °C (85.3 °F at 699.7 hPa)
荧光
λex 460 nm; λem 515 nm(lit.)
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
[Na+].[Na+].[O-]c1ccc2c(Oc3cc([O-])ccc3C24OC(=O)c5ccccc45)c1
InChI
1S/C20H12O5.2Na/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20;;/h1-10,21-22H;;/q;2*+1/p-2
InChI key
RGPLGPBQJOQFJS-UHFFFAOYSA-L
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一般描述
荧光素是一种黄嘌呤染料,是生物学中常用的标记试剂。
应用
水溶性荧光染料由于其分子半径小,渗透性和血管灌注研究中得到应用。 以荧光素钠作为荧光示踪剂,用于研究血脑屏障(BBB)和血脊髓屏障(BSCB)在啮齿类动物模型中的通透性。 以该染料为探针底物,研究了有机阴离子转运多肽(OATP)介导的肝细胞药物转运。荧光素钠还被应用于光致退色后 原位 溶质通过荧光恢复进入骨内。
荧光素钠盐被用作一种溶质,用于研究微血管渗透性。它已被用作研究血液屏障穿透性的测试分子。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
423.7 °F - Pensky-Martens closed cup
闪点(°C)
217.6 °C - Pensky-Martens closed cup
个人防护装备
Eyeshields, Gloves, type N95 (US)
从最新的版本中选择一种:
Physiological research, 52(5), 607-614 (2003-10-11)
The aim was to study the blood-brain permeability according to the distribution in the rat brain of Evans blue (EB) and sodium fluorescein (NaFl) administered by an intracarotid injection. Eighteen animals were divided into six groups according to the state
Temperature dependence of electronic parameters of organic Schottky diode based on fluorescein sodium salt.
Synthetic Metals, 161(9), 881-887 (2011)
The Journal of physiology, 543(Pt 3), 959-975 (2002-09-17)
The permeability, P(S), to sodium fluorescein (Stokes-Einstein radius = 0.45 nm) has been measured in single mesenteric capillaries of pithed frogs and anaesthetised rats as perfusion velocity, U, was varied over a range from 400 up to 2000-10,000 microm s(-1).
In vitro model of the outer blood-retina barrier.
Brain Research. Brain Research Protocols, 13, 26-26 (2004)
Structural mechanisms of acute VEGF effect on microvessel permeability.
American Journal of Physiology. Heart and Circulatory Physiology, 284, H2124-H2124 (2003)
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