推荐产品
等级
pharmaceutical primary standard
API类
flutrimazole
制造商/商品名称
EDQM
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
Fc1c(cccc1)C([n]4cncc4)(c3ccc(cc3)F)c2ccccc2
InChI
1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H
InChI key
QHMWCHQXCUNUAK-UHFFFAOYSA-N
相关类别
一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Flutrimazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
A Alomar et al.
Dermatology (Basel, Switzerland), 190(4), 295-300 (1995-01-01)
Flutrimazole is a new imidazole derivate. Its antifungal activity has been demonstrated in in vivo and in vitro studies to be comparable to that of clotrimazole and higher than bifonazole. To compare the efficacy and tolerability of flutrimazole cream 1%
del Palacio et al.
Mycoses, 38(9-10), 395-403 (1995-09-01)
In a double-blind, randomized study the efficacy and tolerance of flutrimazole 1% solution were compared with bifonazole 1% solution, applied once daily for 4 weeks, in 40 patients with culturally proven dermatophytosis or cutaneous candidosis. Forty patients with mycologically proven
Synthesis and antifungal activity of a series of difluorotritylimidazoles.
J Bartrolí et al.
Arzneimittel-Forschung, 42(6), 832-835 (1992-06-01)
In vitro and in vivo studies with flutrimazole, a new imidazole derivative with antifungal activity.
J García Rafanell et al.
Arzneimittel-Forschung, 42(6), 836-840 (1992-06-01)
1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole (flutrimazole, UR-4056, CAS 119006-77-8) is a new topical imidazole antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts, saprophytic and pathogenic to animals and humans (MIC = 0.025-5.0 micrograms/ml). In most of these
O Binet et al.
Mycoses, 37(11-12), 455-459 (1994-11-01)
In a multicentre, double-blind, randomized, parallel group clinical trial, the efficacy and tolerability of flutrimazole 1% dermal cream were compared with those of a reference compound, clotrimazole 1% dermal cream, applied topically twice daily for 4 weeks in patients with
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