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Merck
CN

F0060000

Fenticonazole nitrate

European Pharmacopoeia (EP) Reference Standard

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About This Item

经验公式(希尔记法):
C24H21Cl2N3O4S
CAS号:
分子量:
518.41
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

fenticonazole

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

InChI

1S/C24H20Cl2N2OS.HNO3/c25-19-8-11-22(23(26)14-19)24(15-28-13-12-27-17-28)29-16-18-6-9-21(10-7-18)30-20-4-2-1-3-5-20;2-1(3)4/h1-14,17,24H,15-16H2;(H,2,3,4)

InChI key

FJNRUWDGCVDXLU-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Fenticonazole nitrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

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Silvia Adriana Lopez-De-Blanc et al.
Medicina oral : organo oficial de la Sociedad Espanola de Medicina Oral y de la Academia Iberoamericana de Patologia y Medicina Bucal, 7(4), 260-270 (2002-07-23)
The aim of the present paper was to evaluate the effect of fenticonazole and to compare it with that of ketoconazole and nystatin in the topical treatment of oral chronic candidosis. Eighty patients diagnosed with erythematous chronic candidosis were divided
J Fernández-Alba et al.
Journal of chemotherapy (Florence, Italy), 16(2), 179-186 (2004-06-26)
Because of its potential as a low cost first-line monotherapy for the most common vulvovaginal infections, we evaluated fenticonazole nitrate in a prospective, open-label, multicenter pilot study with 101 sexually active women (per-protocol; 16 to 61 years of age) with
M G Quaglia et al.
Chirality, 14(5), 449-454 (2002-05-02)
Fenticonazole is a chiral antifungal agent, used in therapy as the racemic mixture. The investigation on the chirality of fenticonazole is reported in this study. rac-Fenticonazole was resolved by HPLC and by capillary electrophoresis (CE). The chiral stationary phase (CSP)
Stefano Veraldi et al.
Drugs, 68(15), 2183-2194 (2008-10-09)
Fenticonazole is an imidazole derivative with a broad spectrum of antimycotic activity against dermatophytes and yeasts in in vitro and clinical studies. Fenticonazole exerts its unique antimycotic mechanism of action in the following three ways: (i) inhibition of the secretion
St Kovachev et al.
Akusherstvo i ginekologiia, 48(6), 18-23 (2009-01-01)
The aim of this study is to investigate the effectiveness of single-day treatment with oral fluconazole and topical fenticonazole in acute vulvovaginal candidosis (VVC). Infection was proven by detection of yeast cells and pseudohyphae on microscopic examination of vaginal wet

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