所有图片(2)
别名:
(-)- 顺 -2-(3,4,5-三羟基苯基)-3,4-二氢-1 (2 H )-苯并吡喃-3,5,7-三醇, (-)-cis-3,3′,4′,5,5′,7-Hexahydroxyflavane
经验公式（希尔记法）:
C15H14O7
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生物来源
green tea
质量水平
检测方案
≥95% (HPLC)
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
2-8°C
SMILES字符串
O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c(O)c3
InChI
1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15-/m1/s1
InChI key
XMOCLSLCDHWDHP-IUODEOHRSA-N
基因信息
human ... CYP1A2(1544)
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一般描述
(−)-表没食子儿茶素是绿茶中最主要的儿茶素成分之一，也是含量最丰富(~20%)的一种，具有抗氧化特性。
应用
(−)-表没食子儿茶素(EGC)已用于：
- 作为高效液相色谱(HPLC)分析的参考标准品
- 分析其对α-淀粉酶和α-葡糖苷酶的抑制作用，以便控制糖尿病的餐后高血糖
- 在细胞活力检测中检查其对鼠类胰腺β-细胞的抗铁死亡和铁毒性的保护作用
- 评估其对长期急性和慢性降植烷诱导关节炎的潜在抗炎影响
- 处理怀孕和哺乳小鼠，研究其对体外血管生成、增殖和内皮细胞迁移的影响
- 根据CD4+（分化簇4）和CD8+（分化簇8）细胞数量，评估其对怀孕和哺乳小鼠脾脏的影响
生化/生理作用
(−)-表没食子儿茶素(EGC)已证明可用作抗癌剂，对人乳腺癌细胞MCF-7中heregulin-b1(HRG)诱导的迁移/侵袭具有抑制作用。它也对单纯疱疹病毒具有强抗病毒活性。
绿茶多酚。抗癌剂。抗氧化活性低于 EGCG。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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商品
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。
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