所有图片(3)
别名:
EGS, 乙二醇二琥珀酸二（N-琥珀酰亚胺基）酯, 乙二醇双（琥珀酰亚胺琥珀酸酯）, 二（N-琥珀酰亚胺基）乙二醇二琥珀酸酯
经验公式（希尔记法）:
C18H20N2O12
CAS号:
分子量:
456.36
Beilstein:
9167119
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47
推荐产品
形式
powder
质量水平
反应适用性
reagent type: cross-linking reagent
溶解性
acetic acid: water (1:1): ≤50 mg/mL
DMF: soluble
应用
diagnostic assay manufacturing
hematology
histology
储存温度
2-8°C
SMILES字符串
O=C(CCC(=O)ON1C(=O)CCC1=O)OCCOC(=O)CCC(=O)ON2C(=O)CCC2=O
InChI
1S/C18H20N2O12/c21-11-1-2-12(22)19(11)31-17(27)7-5-15(25)29-9-10-30-16(26)6-8-18(28)32-20-13(23)3-4-14(20)24/h1-10H2
InChI key
QLHLYJHNOCILIT-UHFFFAOYSA-N
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应用
乙二醇-双（琥珀酸 N -羟基琥珀酰亚胺酯）已被用作交联剂。
生化/生理作用
乙二醇-双（琥珀酸 N-羟基琥珀酰亚胺酯）是一种同双功能、可裂解交联剂。 主要通过 pH 值为7.5 的(6.5-8.5) 缓冲的酰胺键与含有伯胺的分子偶联。该连接提供了 12 个原子的间隔区。
特点和优势
乙二醇键可被羟胺裂解。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Michael W Wandling et al.
The journal of trauma and acute care surgery, 83(5), 837-845 (2017-10-27)
Patients managed nonoperatively have been excluded from risk-adjusted benchmarking programs, including the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP). Consequently, optimal performance evaluation is not possible for specialties like emergency general surgery (EGS) where nonoperative management
Angela M Ingraham et al.
Annals of surgery, 270(2), 270-280 (2018-04-03)
To examine national adherence to emergency general surgery (EGS) best practices. There is a national crisis in access to high-quality care for general surgery emergencies. Acute care surgery (ACS), a specialty leveraging strengths of trauma systems, may ameliorate this crisis.
Evgeniy V Petrotchenko et al.
Molecular & cellular proteomics : MCP, 4(8), 1167-1179 (2005-05-20)
An emerging approach for studying protein-protein interaction in complexes is the combination of chemical cross-linking and mass spectrometric analysis of the cross-linked peptides (cross-links) obtained after proteolysis of the complex. This approach, however, has several challenges and limitations, including the
Jin-Woo Yang et al.
Scientific reports, 7(1), 8060-8060 (2017-08-16)
Plant homeodomain finger protein 20 (PHF20), a methyl lysine effector protein, is a component MOF-NSL lysine acetyltranferase complex. Global deletion of PHF20 has shown spinal bone defects and reduced skeletal formation. However, the molecular basis of PHF20 involved in skeletal
Da Lin et al.
Nature genetics, 50(5), 754-763 (2018-04-28)
Chromosome conformation capture (3C) technologies can be used to investigate 3D genomic structures. However, high background noise, high costs, and a lack of straightforward noise evaluation in current methods impede the advancement of 3D genomic research. Here we developed a
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