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表单
powder
质量水平
反应适用性
reagent type: cross-linking reagent
颜色
white to off-white
溶解性
acetic acid: water (1:1): ≤50 mg/mL
DMF: soluble
应用
diagnostic assay manufacturing
hematology
histology
储存温度
2-8°C
SMILES字符串
O=C(CCC(=O)ON1C(=O)CCC1=O)OCCOC(=O)CCC(=O)ON2C(=O)CCC2=O
InChI
1S/C18H20N2O12/c21-11-1-2-12(22)19(11)31-17(27)7-5-15(25)29-9-10-30-16(26)6-8-18(28)32-20-13(23)3-4-14(20)24/h1-10H2
InChI key
QLHLYJHNOCILIT-UHFFFAOYSA-N
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应用
乙二醇-双（琥珀酸 N -羟基琥珀酰亚胺酯）已被用作交联剂。
生化/生理作用
乙二醇-双（琥珀酸 N-羟基琥珀酰亚胺酯）是一种同双功能、可裂解交联剂。 主要通过 pH 值为7.5 的(6.5-8.5) 缓冲的酰胺键与含有伯胺的分子偶联。该连接提供了 12 个原子的间隔区。
特点和优势
乙二醇键可被羟胺裂解。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
A Anagnostou et al.
Proceedings of the National Academy of Sciences of the United States of America, 87(15), 5978-5982 (1990-08-01)
Erythropoietin is known to be a hematopoietic growth factor with a singularly specific action on the proliferation and differentiation of erythroid progenitor cells. We have observed a dose-dependent proliferative action of human recombinant erythropoietin on human umbilical vein endothelial cells
Chemical cross-linking and mass spectrometry for mapping three-dimensional structures of proteins and protein complexes.
Sinz A
Journal of Mass Spectrometry : Jms, 38, 1225-1237 (2003)
Stiffened Extracellular Matrix and Signaling from Stromal Fibroblasts via Osteoprotegerin Regulate Tumor Cell Invasion in a 3-D Tumor in Situ Model.
McLane JS and Ligon LA
Cancer Microenvironment, 9, 127-139 (2016)
Kristin DeGirolamo et al.
Canadian journal of surgery. Journal canadien de chirurgie, 61(4), 237-243 (2018-08-02)
Emergency general surgery (EGS) services are gaining popularity in Canada as systems-based approaches to surgical emergencies. Despite the high volume, acuity and complexity of the patient populations served by EGS services, little has been reported about the services' structure, processes
Angela M Ingraham et al.
Annals of surgery, 270(2), 270-280 (2018-04-03)
To examine national adherence to emergency general surgery (EGS) best practices. There is a national crisis in access to high-quality care for general surgery emergencies. Acute care surgery (ACS), a specialty leveraging strengths of trauma systems, may ameliorate this crisis.
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