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Merck
CN

E1680000

雌三醇

European Pharmacopoeia (EP) Reference Standard

别名:

1,3,5(10)-三烯-3β,16α,17β-三醇, 16,17-二羟甾醇, 雌激素三醇

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关于此项目

经验公式(希尔记法):
C18H24O3
化学文摘社编号:
分子量:
288.38
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2508172
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产品名称

雌三醇, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1

SMILES string

C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@@H](O)[C@@H]2O

InChI key

PROQIPRRNZUXQM-ZXXIGWHRSA-N

grade

pharmaceutical primary standard

API family

estriol

manufacturer/tradename

EDQM

mp

280-282 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Estriol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Elisa Holm et al.
Maturitas, 78(4), 293-297 (2014-06-18)
To assess the patterns of use of reimbursed systemic hormone therapy (HT) and vaginal estrogen preparations among women aged 45 and older in Finland. Reimbursed purchases of prescribed systemic HT and vaginal estrogen preparations for the years 2003-2012 were obtained
T M Goodwin
American journal of obstetrics and gynecology, 180(1 Pt 3), S208-S213 (1999-01-23)
Although estriol has been studied as an indicator of fetal well-being in the past, its broader biologic role has not been elucidated. Estriol in the maternal compartment closely reflects fetal adrenal activity, and increased fetal adrenal activity prior to the
Unconventional estrogens: estriol, biest, and triest.
M Taylor
Clinical obstetrics and gynecology, 44(4), 864-879 (2001-10-16)
G P Vooijs et al.
European journal of obstetrics, gynecology, and reproductive biology, 62(1), 101-106 (1995-09-01)
To gain more insight into whether intravaginal treatment of local urogenital complaints with the mild-acting oestrogen estriol is capable of inducing proliferation of the endometrium, the results of the clinical studies that have been published over the years have been
Patrick S Ramsey et al.
Clinics in perinatology, 30(4), 701-733 (2004-01-13)
Preterm birth is a major complication of pregnancy and remains a leading cause of neonatal morbidity and mortality worldwide. Improvements in the authors' understanding of the pathophysiology of preterm labor have led to the development of novel diagnostic tools of

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