推荐产品
等级
analytical standard, for drug analysis
质量水平
检测方案
≥90% (HPLC)
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
94-96 °C (dec.) (lit.)
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
格式
neat
储存温度
2-8°C
SMILES字符串
CCO\C=C1/N=C(OC1=O)c2ccccc2
InChI
1S/C12H11NO3/c1-2-15-8-10-12(14)16-11(13-10)9-6-4-3-5-7-9/h3-8H,2H2,1H3/b10-8-
InChI key
SJHPCNCNNSSLPL-NTMALXAHSA-N
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应用
4-乙氧基亚甲基-2-苯基-2-恶唑啉-5-酮已被用作半抗原化试剂，可在成年斑马鱼肠组织中诱导炎症反应，这可用作克罗恩病和溃疡性结肠炎等两种形式炎症性肠病的基因表达研究的模型。
有关合适仪器技术的更多信息，请参考产品的分析证书。如需进一步支持，请联系技术服务。
生化/生理作用
噁唑酮敏化剂
Amalie W Arildsen et al.
Frontiers in immunology, 12, 650621-650621 (2021-04-06)
Epidemiological studies have long reported that perturbations of the childhood microbiome increase the risk of developing allergies, but a causal relationship with atopic dermatitis remains unclear. Here we colonized germ-free mice at birth or at one or eight week-of-age to
Ann Laigaard et al.
Scientific reports, 10(1), 21204-21204 (2020-12-05)
Atopic dermatitis is a chronic eczema commonly observed among children in Western countries. The gut microbiota is a significant factor in the pathogenesis, and ways to promote intestinal colonizers with anti-inflammatory capabilities are therefore favorable. The present study addressed the
Comparison of two chemically-induced colitis-models in adult zebrafish, using optical projection tomography and novel transcriptional markers
Haarder S, et al.
The Open Immunology Journal, 6, 154-154 (2016)
Zenghui Lu et al.
The Journal of organic chemistry, 77(21), 9871-9877 (2012-10-11)
A novel palladium-catalyzed approach for the assembly of 3,4,5-trisubstituted oxazolones has been achieved by the coupling of N-alkynyl tert-butyloxycarbamates with aryl halides and related electrophiles, which involves an oxidative addition followed by oxypalladation/reductive elimination. The reaction provides a convenient access
Joanne C Masterson et al.
Gut, 63(1), 43-53 (2012-11-20)
Eosinophilic oesophagitis (EoE) is a chronic inflammatory condition of the oesophagus with limited treatment options. No previous transgenic model has specifically targeted the oesophageal mucosa to induce oesophageal eosinophilia. We developed a mouse model that closely resembles EoE by utilising
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