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经验公式(希尔记法):
C13H16N4O2
化学文摘社编号:
分子量:
260.29
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
226-333-3
Beilstein/REAXYS Number:
258464
MDL number:
产品名称
敌菌净, analytical standard, ≥99.0% (TLC)
InChI key
LDBTVAXGKYIFHO-UHFFFAOYSA-N
InChI
1S/C13H16N4O2/c1-18-10-4-3-8(6-11(10)19-2)5-9-7-16-13(15)17-12(9)14/h3-4,6-7H,5H2,1-2H3,(H4,14,15,16,17)
SMILES string
COc1ccc(Cc2cnc(N)nc2N)cc1OC
grade
analytical standard
assay
≥99.0% (TLC)
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
Gene Information
rat ... Dhfr(24312)
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves
Residue Reviews: Residues of Pesticides and Other Contaminants in the Total Environment (2012)
G Gigler et al.
Agents and actions. Supplements, 32, 39-43 (1991-01-01)
The compound EGIS-5645 is a potent antipyretic agent possessing analgesic and antiinflammatory properties. The drug is active in antiinflammatory models such as carrageenin oedema and adjuvant arthritis. EGIS-5645 shows practically no gastro-ulcerogenic effect. The molecule does not inhibit either prostaglandin
H Yoshimura
Mutation research, 261(2), 149-152 (1991-10-01)
The coccidiostat diaveridine was tested for mutagenicity in the Salmonella/microsome assay with tester strains TA100 and TA98. This compound was not mutagenic in either tester strain in the presence and absence of rat S9 mix, but was found to be
P D Walzer et al.
Antimicrobial agents and chemotherapy, 32(1), 96-103 (1988-01-01)
Inhibitors of folic acid synthesis were compared alone and in different combinations in the therapy of pneumocystosis in immunosuppressed rats. Sulfonamides (sulfamethoxazole, sulfadiazine, and sulfadoxine) and sulfones (dapsone) used alone were very active against Pneumocystis carinii, as judged by histologic
Tomoko Ono-Ogata et al.
Environmental and molecular mutagenesis, 39(1), 43-48 (2002-01-29)
We examined the mutagenic activities of six antiprotozoal drugs (three diaminopyrimidine compounds [pyrimethamine, diaveridine, and trimethoprim] and three 8-aminoquinoline derivatives [primaquine, pentaquine, and pamaquine]) in Escherichia coli WP2uvrA/pKM101 and Salmonella typhimurium TA100 and TA98 with and without nitrite treatment. The
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