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Merck
CN

D8255

1,4-二硫代赤藓醇

≥99.0%

别名:

DTE, 二硫代赤丁四醇, 克莱兰氏试剂, 赤式1,4-二巯基-2,3-丁二醇

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关于此项目

线性分子式:
HSCH2CH(OH)CH(OH)CH2SH
化学文摘社编号:
分子量:
154.25
UNSPSC Code:
12352201
NACRES:
NA.21
PubChem Substance ID:
EC Number:
229-998-8
Beilstein/REAXYS Number:
1719756
MDL number:
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产品名称

1,4-二硫代赤藓醇, ≥99.0%

InChI key

VHJLVAABSRFDPM-ZXZARUISSA-N

InChI

1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4+

SMILES string

O[C@@H](CS)[C@H](O)CS

assay

≥99.0%

form

powder

reaction suitability

reagent type: reductant

pH

4.5-6.5 (25 °C, 15.4 g/L)

mp

82-84 °C (lit.)

storage temp.

2-8°C

Quality Level

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Application

用于将 −SH 基保持在还原态的试剂;定量还原二硫化物。

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

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Colin M Cleary et al.
eLife, 9 (2020-09-15)
Respiratory chemoreceptors regulate breathing in response to changes in tissue CO2/H+. Blood flow is a fundamental determinant of tissue CO2/H+, yet little is known regarding how regulation of vascular tone in chemoreceptor regions contributes to respiratory behavior. Previously, we showed
Muzamil M Z Noorani et al.
Frontiers in physiology, 2, 42-42 (2011-08-04)
Transient receptor potential (TRP) C1 and C3 (TRPC1 and TRPC3) are expressed in vascular smooth muscle cells and are thought to be involved in vascular contractility. In the present study, we determined the effect of systemic hypertension on TRPC1/TRPC3 channel
Christopher J Garland et al.
Science signaling, 10(486) (2017-07-06)
Vascular smooth muscle contraction is suppressed by feedback dilation mediated by the endothelium. In skeletal muscle arterioles, this feedback can be activated by Ca2+ signals passing from smooth muscle through gap junctions to endothelial cells, which protrude through holes in
Vishal R Yadav et al.
American journal of physiology. Lung cellular and molecular physiology, 314(5), L724-L735 (2018-02-02)
Hypoxia-induced pulmonary vasoconstriction (HPV) is attributed to an increase in intracellular Ca2+ concentration ([Ca2+]i) in pulmonary artery smooth muscle cells (PASMCs). We have reported that phospholipase C-γ1 (PLCγ1) plays a significant role in the hypoxia-induced increase in [Ca2+]i in PASMCs
András Kolozsi et al.
Inorganic chemistry, 47(9), 3832-3840 (2008-04-03)
The aqueous solutions of arsenous acid with the meso and racemic forms of 1,4-dithiol-butane-2,3-diol, namely, dithioerythritol (dte) and dithiothreitol (dtt), respectively, were titrated pH-metrically in different molar ratios. The p K a values determined for As(OH) 3, and dtt were

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