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主要文件

D6924

Sigma-Aldrich

硫酸葡聚糖 钠盐 来源于明串珠菌 属

average mol wt 9,000-20,000

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About This Item

CAS号:
9011-18-1
MDL编号:
MFCD00081551
UNSPSC代码:
12352201
NACRES:
NA.21

生物来源

bacterial (Leuconostoc mesenteroides)

质量水平

200

表单

powder

旋光性

[α]/D 90 to 105 °, c = 6% (w/v)

分子量

average mol wt 9,000-20,000

组成

Sulfur Content, 16.0-19.0%

颜色

white to off-white

有效pH范围

5.5 - 8.0

溶解性

H2O: 100 mg/mL

储存温度

room temp

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相关类别

一般描述

葡聚糖硫酸钠是α-1,6-D-吡喃葡萄糖的天然聚合物。它是一种亲水性、可生物降解和生物相容性的聚阴离子聚合物。这种高度分枝的多糖具有1,6和1,4糖苷键，每个糖基单位由2.3个硫酸盐基组成。

应用

来自明串珠菌属的右旋糖酐硫酸钠已用于：
  • 评价硫酸盐聚糖参与重组人前顶蛋白/顶蛋白与透明带（ZP）糖蛋白相互作用
  • 将胚胎第5天的小鸡胚胎注射入玻璃体腔，以评估眼睛大小，并研究其对视网膜细胞增殖的影响
  • 检测TNF-刺激基因6（TSG-6）与固定化透明质酸（HA）结合的结构特异性

生化/生理作用

硫酸右旋糖酐可能具有抗凝血和抗病毒的特性。它还有助于降低胆固醇水平。在医疗领域广泛用作血浆体积膨胀剂和纤溶剂。硫酸右旋糖酐也可用作壳聚糖的交联剂。

其他说明

为了全面了解我们针对客户研究提供的各种葡聚糖产品，建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
0000401914
0000368311
0000351612
0000308299
0000304916

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the sulfate content of Product D6924, Dextran sulfate sodium salt?

    The sulfate content is approximately 17%, which corresponds to two sulfate groups per glucose unit.

  4. Can solutions of Product D6924, Dextran sulfate sodium salt, be autoclaved?

    Neutral solutions of dextran sulfate may be sterilized by autoclaving at 110-115°C for 30 minutes.

  5. What is the average molecular weight for Product D6924, Dextran sulfate sodium salt?

    The average molecular weight can vary from lot-to-lot. Lot number 068K1121 has an average molecular weight of 15.6 kDa.

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Laura I Furlong et al.
Fertility and sterility, 83(6), 1780-1790 (2005-06-14)
To characterize proacrosin/acrosin interaction with isolated zona pellucida (ZP) components. Prospective study. Basic research laboratory. Recombinant proteins derived from human proacrosin (Rec-40, Rec-30, Rec-20, Rec-10, and Rec-6) and from human ZP glycoproteins (rec-hZPA, ZPB, and ZPC). In vitro binding assay
Hans-Georg Wisniewski et al.
The Journal of biological chemistry, 280(15), 14476-14484 (2005-02-09)
TSG-6 protein, up-regulated in inflammatory lesions and in the ovary during ovulation, shows anti-inflammatory activity and plays an essential role in female fertility. Studies in murine models of acute inflammation and experimental arthritis demonstrated that TSG-6 has a strong anti-inflammatory
Osama A Madkhali et al.
Scientific reports, 11(1), 9914-9914 (2021-05-12)
The purpose of this study was to develop a novel nano antibacterial formulation of dextran sulfate sodium polymer. The dextran sulfate sodium (DSS) nanoparticles were formulated with gelation technique. The nanoparticles exhibited significant physicochemical and effective antibacterial properties, with zeta
Willi Halfter
Investigative ophthalmology & visual science, 49(8), 3289-3298 (2008-03-26)
The vitreous body (VB) is a transparent, extracellular matrix structure that fills the vitreous cavity of the eye. Major constituents of the VB are hyaluronic acid (HA) and glycosaminoglycans (GAGs), both of which are highly charged, linear carbohydrate polymers. The
Yi-Nan Zhang et al.
ACS nano, 14(8), 9478-9490 (2020-06-02)
Nanovaccines need to be transported to lymph node follicles to induce humoral immunity and generate neutralizing antibodies. Here, we discovered that subcapsular sinus macrophages play a barrier role to prevent nanovaccines from accessing lymph node follicles. This is illustrated by
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实验方案

Dextran Sulfate

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

硫酸葡聚糖

硫酸葡聚糖以钠盐形式供应，使其在水中可溶且稳定。硫酸葡聚糖含有大约17%的硫，相当于每个葡糖基残基大约有2.3个硫酸基团。

相关内容

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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