D6001
硫酸葡聚糖 钠盐 来源于明串珠菌 属
average mol wt >500,000 (dextran starting material), contains 0.5-2.0% phosphate buffer, pH 6-8
useful pH range
6.0-8.0 (1% in water)
biological source
bacterial (Leuconostoc mesenteroides)
form
powder
optical activity
[α]/D 90 to 105 °, c = 6% (w/v) in water
mol wt
average mol wt >500,000 (dextran starting material)
contains
0.5-2.0% phosphate buffer, pH 6-8
composition
Sulfur Content, 16.0-19.0%
color
white to off-white
solubility
H2O: 100 mg/mL
Quality Level
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General description
硫酸葡聚糖是带负电荷的硫酸化多糖， 可由葡聚糖与氯磺酸的酯化反应产生。具有抗病毒、抗凝血和佐剂特性。葡聚糖用于治疗出血、烧伤、手术伤口和创伤。可以增加血流量，阻断红细胞聚集。葡聚糖降低血栓形成和术后肺栓塞风险。作为核糖核酸酶抑制剂发挥作用。
Application
从明串珠菌属某些种（Leuconostoc spp）中提取的硫酸葡聚糖钠盐可用于：
- 使含脂肪的血浆脱脂（67）（70）
- 诱发啮齿类动物远端结肠发生炎症和致癌反应（68）
- 制备3,4-乙撑二氧噻吩（EDOT）（69）
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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实验方案
Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.
硫酸葡聚糖以钠盐形式供应，使其在水中可溶且稳定。硫酸葡聚糖含有大约17%的硫，相当于每个葡糖基残基大约有2.3个硫酸基团。
相关内容
Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.
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