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Merck
CN

D172405

Sigma-Aldrich

N,N-二甲基-4-亚硝基苯胺

97%, powder or chunks

别名:

4-亚硝基-N,N-二甲基苯胺

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About This Item

线性分子式:
ONC6H4N(CH3)2
CAS号:
分子量:
150.18
Beilstein:
607293
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

产品名称

N,N-二甲基-4-亚硝基苯胺, ≥97%

质量水平

方案

≥97%

表单

powder or chunks

mp

85-87 °C (lit.)

溶解性

ethanol: 5% (green to very dark green)

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

CN(C)c1ccc(cc1)N=O

InChI

1S/C8H10N2O/c1-10(2)8-5-3-7(9-11)4-6-8/h3-6H,1-2H3

InChI key

CMEWLCATCRTSGF-UHFFFAOYSA-N

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应用

N,N-二甲基-4-亚硝基苯胺与咪唑一起用于检测细胞中单线态氧的形成。

生化/生理作用

N,N-二甲基-4-亚硝基苯胺用于检测单线态氧。单线态氧与咪唑反应,并通过氧化作用漂白 N,N-二甲基-4-亚硝基苯胺。漂白N,N-二甲基-4-亚硝基苯胺会在 438 nm 处观察到吸收减少。

象形图

FlameSkull and crossbones

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2 - Self-heat. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

4.2 - Pyrophoric and self-heating hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Abdullah Shafique Ahmad et al.
Toxicological sciences : an official journal of the Society of Toxicology, 89(1), 265-270 (2005-10-21)
The clinical side effects associated with the inhibition of cyclooxygenase enzymes under pathologic conditions have recently raised concerns. A better understanding of neuroinflammatory mechanisms and neuronal survival requires knowledge of cyclooxygenase downstream pathways, especially PGE2 and its G-protein-coupled receptors. In
Zhuo Chen et al.
Environmental science & technology, 40(23), 7290-7297 (2006-12-22)
This paper presents mechanistic studies on the formation of NDMA, a newly identified chloramination disinfection byproduct, from reactions of monochloramine with natural organic matter. A kinetic model was developed to validate proposed reactions and to predict NDMA formation in chloraminated
Elif Pehlivanoglu-Mantas et al.
Water research, 40(6), 1287-1293 (2006-03-01)
To assess the stability of precursors of the chloramine disinfection byproduct N-nitrosodimethylamine (NDMA) under conditions expected in effluent-dominated surface waters, effluent samples from four municipal wastewater treatment plants were subjected to chlorination and chloramination followed by incubation in the presence
Juliette Gafni et al.
Toxicological sciences : an official journal of the Society of Toxicology, 77(1), 72-82 (2003-11-06)
The mechanisms by which non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) and rapamycin interact with ryanodine receptor (RyR) complexes to alter Ca2+ signaling, were explored in intact cerebellar granule neurons. PCB 95 (10 microM, 20 min) significantly increased the number of neurons responding
Vassilis L Souliotis et al.
Mutation research, 568(2), 155-170 (2004-11-16)
Following administration to rats of various doses of N-nitrosodimethylamine (NDMA), O(6)-methylguanine (O(6)-meG) was lost from the DNA of four tissues (liver, white blood cells, lymph nodes, bone marrow) over two, sharply demarcated phases with substantially differing repair rates. Repair during

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