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Merck
CN

D0501

4-脱氧吡哆醇 盐酸盐

analytical standard

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关于此项目

经验公式(希尔记法):
C8H11NO2 · HCl
化学文摘社编号:
分子量:
189.64
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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生物来源

synthetic (organic)

质量水平

等级

analytical standard

方案

≥98%

技术

HPLC: suitable
gas chromatography (GC): suitable

颜色

white to yellow

mp

263-265 °C

应用

forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products

包装形式

neat

储存温度

−20°C

SMILES字符串

Cl.Cc1ncc(CO)c(C)c1O

InChI

1S/C8H11NO2.ClH/c1-5-7(4-10)3-9-6(2)8(5)11;/h3,10-11H,4H2,1-2H3;1H

InChI key

QZKKOQQIVLXUEI-UHFFFAOYSA-N

一般描述

4-脱氧吡哆醇盐酸盐是维生素 B6 的强效拮抗剂。

应用

4-脱氧吡哆醇盐酸盐分析标准品的用途如下:
  • 开发反相高效液相色谱 (RP-HPLC)-质谱 (MS) 方法联用检测,进行美他多辛药物的杂质分析
  • 用作超高效和高效液相色谱分析的内标,与紫外、质谱和荧光检测器联用分析复合维生素片剂样品中的吡哆醇

其他说明

有关合适的仪器技术的更多信息,请参阅产品′的检验报告。想要获得更多支持,请联系技术服务部。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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W F Wolkers et al.
The Journal of biological chemistry, 266(31), 20761-20766 (1991-11-05)
The distances between enzyme-bound paramagnetic CrATP (a stable, beta, gamma-bidentate complex of Cr3+ and ATP) at the active site of sheep brain pyridoxal kinase and the protons of bound inhibitor 4-dPyr (4-deoxypyridoxine) were determined in the ternary enzyme-CrATP.4-dPyr complex by
T Mizote et al.
Microbiology (Reading, England), 142 ( Pt 10), 2969-2974 (1996-10-01)
Extracts from Escherichia coli K-12 contained two distinct enzymes capable of catalysing the phosphorylation of hydroxymethylpyrimidine (HMP) to HMP monophosphate: pyridoxine kinase (EC 2.7.1.35) and an enzyme that has not previously been genetically analysed, HMP kinase (EC 2.7.1.49). Two distinct
E J Sinkeldam et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 26(3), 195-203 (1988-03-01)
The effect of vitamin E, folic acid, pyridoxine (vitamin B6) and choline on the reduction in circulating lymphocytes in the blood of rats fed Caramel Colour (III) also known as ammonia caramel colour (beer type; AC) has been examined. It
M Lorenzato et al.
Methods and findings in experimental and clinical pharmacology, 9(10), 649-656 (1987-10-01)
The study was performed with isolated perfused isovolumic rat hearts. After a 40 min stabilization period, the effect of 4-deoxypyridoxine (DOP) 10(-5) M was studied with 3 Glc concentrations: 0, 3.3 and 11 mM. DOP was perfused during a 20
N E Andén et al.
Pharmacology & toxicology, 60(5), 393-396 (1987-05-01)
Experimentally induced changes in the concentration of GABA were studied in regions where GABA is present, predominantly in nerve terminals (substantia nigra, pituitary gland) or outside nerve terminals (corpus callosum). Some other regions (cerebellum, cuneate nucleus, corpus striatum, hippocampus) were

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