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Merck
CN

D0501

4-脱氧吡哆醇 盐酸盐

analytical standard

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经验公式(希尔记法):
C8H11NO2 · HCl
化学文摘社编号:
分子量:
189.64
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
205-714-8
MDL number:
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InChI

1S/C8H11NO2.ClH/c1-5-7(4-10)3-9-6(2)8(5)11;/h3,10-11H,4H2,1-2H3;1H

InChI key

QZKKOQQIVLXUEI-UHFFFAOYSA-N

SMILES string

Cl.Cc1ncc(CO)c(C)c1O

biological source

synthetic (organic)

grade

analytical standard

assay

≥98%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

color

white to yellow

mp

263-265 °C

application(s)

forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

−20°C

Quality Level

General description

4-脱氧吡哆醇盐酸盐是维生素 B6 的强效拮抗剂。

Application

4-脱氧吡哆醇盐酸盐分析标准品的用途如下:
  • 开发反相高效液相色谱 (RP-HPLC)-质谱 (MS) 方法联用检测,进行美他多辛药物的杂质分析
  • 用作超高效和高效液相色谱分析的内标,与紫外、质谱和荧光检测器联用分析复合维生素片剂样品中的吡哆醇

Other Notes

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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T Mizote et al.
Microbiology (Reading, England), 142 ( Pt 10), 2969-2974 (1996-10-01)
Extracts from Escherichia coli K-12 contained two distinct enzymes capable of catalysing the phosphorylation of hydroxymethylpyrimidine (HMP) to HMP monophosphate: pyridoxine kinase (EC 2.7.1.35) and an enzyme that has not previously been genetically analysed, HMP kinase (EC 2.7.1.49). Two distinct
Hong Chen et al.
Fish & shellfish immunology, 19(3), 241-252 (2005-04-12)
A feeding experiment was conducted to investigate the effects of dietary pyridoxine (PN) on the immune responses of abalone, Haliotis discus hannai Ino. Purified diets supplemented with 0, 40, 800 mg PN kg(-1) or 80 mg kg(-1) of 4-deoxypyridoxine (PN
M Lorenzato et al.
Methods and findings in experimental and clinical pharmacology, 9(10), 649-656 (1987-10-01)
The study was performed with isolated perfused isovolumic rat hearts. After a 40 min stabilization period, the effect of 4-deoxypyridoxine (DOP) 10(-5) M was studied with 3 Glc concentrations: 0, 3.3 and 11 mM. DOP was perfused during a 20
W F Wolkers et al.
The Journal of biological chemistry, 266(31), 20761-20766 (1991-11-05)
The distances between enzyme-bound paramagnetic CrATP (a stable, beta, gamma-bidentate complex of Cr3+ and ATP) at the active site of sheep brain pyridoxal kinase and the protons of bound inhibitor 4-dPyr (4-deoxypyridoxine) were determined in the ternary enzyme-CrATP.4-dPyr complex by
N E Andén et al.
Pharmacology & toxicology, 60(5), 393-396 (1987-05-01)
Experimentally induced changes in the concentration of GABA were studied in regions where GABA is present, predominantly in nerve terminals (substantia nigra, pituitary gland) or outside nerve terminals (corpus callosum). Some other regions (cerebellum, cuneate nucleus, corpus striatum, hippocampus) were

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