C9231
羧苄青霉素 二钠
meets USP testing specifications
别名:
羧苄青霉素 二钠盐, α-Carboxybenzylpenicillin disodium salt 二钠盐
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关于此项目
经验公式（希尔记法）:
C17H16N2Na2O6S
化学文摘社编号:
分子量:
422.36
UNSPSC Code:
51102829
NACRES:
NA.76
PubChem Substance ID:
EC Number:
225-360-8
Beilstein/REAXYS Number:
5722128
MDL number:
Quality Level
agency
USP/NF, meets USP testing specifications
form
solid
solubility
H2O: 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
application(s)
pharmaceutical (small molecule)
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)c3ccccc3)C(=O)N2[C@H]1C([O-])=O
InChI
1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1
InChI key
RTYJTGSCYUUYAL-YCAHSCEMSA-L
General description
Chemical structure: β-lactam
Application
Used for selection of ampr transformed cells. Used to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.
Biochem/physiol Actions
作用机制：羧青霉素抗生素，可通过灭活细菌细胞膜内表面的转肽酶来抑制细菌细胞壁合成（肽聚糖交联）。
抗微生物谱：具有抗革兰氏阳性和革兰氏阴性细菌活性。
抗微生物谱：具有抗革兰氏阳性和革兰氏阴性细菌活性。
Analysis Note
在 37°C 下可稳定保存 3 天
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
涉药品监管产品
此项目有
Steven D Brown et al.
Biochemistry, 48(47), 11155-11157 (2009-10-24)
Bacteriophage Qbeta coat protein forms uniform virus-like particles when expressed recombinantly in a variety of organisms. We have inserted the IgG-binding Z domain at the carboxy terminus of the coat protein and coexpressed this chimeric subunit with native coat protein
Lintao Zeng et al.
Chemical communications (Cambridge, England), 46(14), 2435-2437 (2010-04-10)
A fluorescent probe (QA) based on quinine bearing two quaternary ammonium groups and a long hydrophobic chain was synthesized, and it showed highly selective recognition of carbenicillin (a typical beta-lactam antibiotic) in 100% aqueous solution via concerted interactions.
Jiachuan Pan et al.
PloS one, 7(9), e45778-e45778 (2012-10-03)
Bacteria are well known to form dormant persister cells that are tolerant to most antibiotics. Such intrinsic tolerance also facilitates the development of multidrug resistance through acquired mechanisms. Thus persister cells are a promising target for developing more effective methods
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C9231-10G | 04061833610367 |
| C9231-5G | 04061833530351 |
| C9231-1G | 04061833530344 |