C8278
卡比沙明 马来酸盐
analytical standard
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关于此项目
经验公式（希尔记法）:
C16H19ClN2O · C4H4O4
化学文摘社编号:
分子量:
406.86
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
222-498-0
MDL number:
InChI key
GVNWHCVWDRNXAZ-BTJKTKAUSA-N
InChI
1S/C16H19ClN2O.C4H4O4/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-10,16H,11-12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
SMILES string
OC(=O)\C=C/C(O)=O.CN(C)CCOC(c1ccc(Cl)cc1)c2ccccn2
grade
analytical standard
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
Gene Information
human ... HRH1(3269)
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
A Chakrabarti et al.
International journal of clinical pharmacology, therapy, and toxicology, 25(6), 310-312 (1987-06-01)
The efficacy and safety of a new antitussive expectorant drug hexapneumine was compared with that of an already marketed and functionally related clistine in a double-blind, randomized, parallel design clinical trial. A total of 100 patients with cough associated with
D J Hoffman et al.
Journal of pharmaceutical sciences, 72(11), 1342-1344 (1983-11-01)
Capillary gas chromatography using an open tubular fused silica column and NP-FID was applied to the simultaneous analysis of the antihistamine, carbinoxamine, and the antitussive, hydrocodone, in human serum. Carbinoxamine and hydrocodone were extracted into methylene chloride-2-propanol (9:1) under alkaline
Hieronim Jakubowski
Chemistry (Weinheim an der Bergstrasse, Germany), 12(31), 8039-8043 (2006-09-05)
Chemical reactivity of homocysteine thiolactone (HTL) has been implicated in cardiovascular disease. Owing to its aminoacyl-thioester character, HTL undergoes facile electrophilic and nucleophilic reactions at its amino and activated-carboxyl group, respectively. To gain insight into the mechanism of the reactions
Derong Zhu et al.
Talanta, 88, 265-271 (2012-01-24)
This work expanded the knowledge of the use of chemometric experimental design in optimizing of six antihistamines separations by capillary electrophoresis with electrochemiluminescence detection. Specially, central composite design was employed for optimizing the three critical electrophoretic variables (Tris-H(3)PO(4) buffer concentration
Y Jin et al.
Electrophoresis, 19(12), 2119-2123 (1998-10-07)
A study of the chiral separations of antihistamines, including pheniramine, chlorpheniramine, brompheniramine, carbinoxamine and doxylamine in capillary electrophoresis (CE) was accomplished using heparin as a chiral additive (CA) and phosphate buffer as the background electrolyte. Several factors were shown to
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