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Merck
CN

C6272

Supelco

克罗米酚 柠檬酸盐

analytical standard

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别名:
枸橼酸氯米芬
经验公式(希尔记法):
C26H28ClNO · C6H8O7
CAS号:
分子量:
598.08
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

forensics and toxicology
pharmaceutical (small molecule)

格式

neat

SMILES字符串

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CC)CCOc1ccc(cc1)\C(=C(\Cl)c2ccccc2)c3ccccc3

InChI

1S/C26H28ClNO.C6H8O7/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,3-4,19-20H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25+;

InChI key

PYTMYKVIJXPNBD-BTKVJIOYSA-N

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一般描述

Clomiphene is an semisynthetic antiestrogen, widely used in the treatment of infertility by inducing ovulation and stimulating sperm production. It is also used in the treatment of breast cancer.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

其他说明

顺反异构体混合物

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Repr. 1B

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


分析证书(COA)

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已有该产品?

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G Eleftheriou et al.
Clinical and experimental obstetrics & gynecology, 39(4), 535-536 (2013-03-01)
Clomiphene is widely used for inducing ovulation. Evidence for congenital abnormalities, in particular central nervous system defects (CNS-D) and in babies born from clomiphene-induced pregnancies is conflicting. The authors report a case of holoprosencephalia (HPE) in a fetus delivered from
M J Nahuis et al.
Human reproduction (Oxford, England), 27(12), 3577-3582 (2012-09-25)
Laparoscopic electrocautery of the ovaries and ovulation induction with gonadotrophins are both second line treatments for women with clomiphene citrate-resistant polycystic ovary syndrome (PCOS). Long-term follow-up after electrocautery versus ovulation induction with gonadotrophins has demonstrated at least comparable chances for
A method by homemade OH/TSO-PMHS fibre solid-phase microextraction coupling with gas chromatography?mass spectrometry for analysis of antiestrogens in biological matrices
Liu W, et al.
Analytica Chimica Acta, 631(1), 47-53 (2009)
Ritsa Storeng et al.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 132(22), 2494-2499 (2013-01-23)
A possible correlation between hormonal stimulation during treatment of infertility and the risk of cancer of the breast, the ovaries, the cervix or the uterus has been investigated in a number of epidemiological studies. The purpose of this article is
Min Xu et al.
Zhongguo zhen jiu = Chinese acupuncture & moxibustion, 33(3), 213-217 (2013-05-30)
To observe clinical efficacy of plum-blossom needle for follicular maldevelopment (FM). Fifty cases of FM were randomly divided into a plum-blossom needle group and a medication group, 25 cases in each one. In the plum-blossom needle group, the plum-blossom needle

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