推荐产品
产品名称
丁酸氯倍他松, ≥98%
质量水平
方案
≥98%
表单
powder
颜色
white to faint yellow cast
mp
90-100 °C
溶解性
chloroform: 50 mg/mL, clear, faintly yellow
ε (消光系数)
13.4 at 243 nm in chloroform
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
CCCC(=O)O[C@@]1([C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(=O)C[C@]12C)C(=O)CCl
InChI
1S/C26H32ClFO5/c1-5-6-22(32)33-26(21(31)14-27)15(2)11-19-18-8-7-16-12-17(29)9-10-23(16,3)25(18,28)20(30)13-24(19,26)4/h9-10,12,15,18-19H,5-8,11,13-14H2,1-4H3/t15-,18-,19-,23-,24-,25-,26-/m0/s1
InChI key
FBRAWBYQGRLCEK-AVVSTMBFSA-N
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一般描述
Clobetasone butyrate is a corticosteroid.
应用
Clobetasone butyrate has been used as an internal standard for the quantitative assay of clobetasol propionate.
Clobetasone butyrate has been used to analyze its bio-concentration factor (BCF) in Cyprinus carpio.
生化/生理作用
Clobetasone butyrate is a potent topical corticosteroid and is primarily used to treat atopic dermatitis (AD). Low dosage of this drug is used to treat dry eye in Sjogrens syndrome.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
Liquid chromatography--tandem mass spectrometric assay for clobetasol propionate in human serum from patients with atopic dermatitis
Sparidans RW, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 878(23), 2150-2154 (2010)
Fluticasone propionate 0.05% cream once daily versus clobetasone butyrate 0.05% cream twice daily in children with atopic dermatitis
Wolkerstorfer A, et al.
Journal of the American Academy of Dermatology, 39(2), 226-231 (1998)
Community Pharmacy - E-Book: Symptoms Diagnosis and Treatment (2011)
Safety and efficacy of 0.1% clobetasone butyrate eyedrops in the treatment of dry eye in Sjogren syndrome
Aragona P, et al.
European Journal of Ophthalmology, 23(3) (2013)
Uptake and biological effects of synthetic glucocorticoids in common carp (Cyprinus carpio)
Nakayama K, et al.
Marine Pollution Bulletin, 85(2), 370-375 (2014)
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