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关于此项目
经验公式(希尔记法):
C16H16N3NaO7S2
化学文摘社编号:
分子量:
449.43
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
251-574-6
MDL number:
InChI key
GNWUOVJNSFPWDD-XMZRARIVSA-M
InChI
1S/C16H17N3O7S2.Na/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19;/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22);/q;+1/p-1/t14-,16+;/m1./s1
SMILES string
[Na+].CO[C@]2(NC(=O)Cc1cccs1)C3SCC(COC(N)=O)=C(N3C2=O)C([O-])=O
form
powder or granules
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
storage temp.
2-8°C
Quality Level
General description
头孢西丁是一种β内酰胺,属于头孢霉素类抗生素,被认为是第二代头孢菌素。它显示出对β-内酰胺酶的耐药性,并用于治疗由革兰氏阳性和革兰氏阴性细菌引起的广谱细菌感染,如支气管炎、咽炎、脑膜炎和尿路感染等。头孢西丁用于静脉和肌肉注射。已发现它对拟杆菌具有活性,可用于治疗混合好氧-厌氧感染。
Application
分析标准品可用于:
- 在纯剂型和药物剂型的碱性降解产物环境下,使用四种稳定性指示分光光度法测定头孢西丁钠
- 通过高效液相色谱法(HPLC)分离和测定商业药品中的头孢西丁钠
Other Notes
有关合适的仪器技术的更多信息,请参阅产品′的检验报告。想要获得更多支持,请联系技术服务部。
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1B
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
涉药品监管产品
涉药品监管产品
此项目有
Spectrofluorimetric analysis of cefoxitin in pharmaceutical dosage
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Methicillin-resistant Staphylococcus aureus screening by online immunometric monitoring of bacterial growth under selective pressure.
Stenholm T, et al.
Antimicrobial Agents and Chemotherapy, 53(12), 5088-5094 (2009)
Analysis of binary mixtures of cephalothin and cefoxitin by using first-derivative spectrophotometry
Murillo.A.J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 14(3), 257-266 (1996)
Antibiotic and chemotherapy e-book, 14(3), 257-266 (2010)
Olga Snitser et al.
Nature communications, 11(1), 6038-6038 (2020-11-29)
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is threatening public health as it spreads worldwide across diverse environments. Its genetic hallmark, the mecA gene, confers resistance to many β-lactam antibiotics. Here, we show that, in addition, mecA provides a broad selective advantage
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