形式
powder or granules
质量水平
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
储存温度
2-8°C
SMILES字符串
[Na+].CO[C@]2(NC(=O)Cc1cccs1)C3SCC(COC(N)=O)=C(N3C2=O)C([O-])=O
InChI
1S/C16H17N3O7S2.Na/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19;/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22);/q;+1/p-1/t14-,16+;/m1./s1
InChI key
GNWUOVJNSFPWDD-XMZRARIVSA-M
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一般描述
头孢西丁是一种β内酰胺,属于头孢霉素类抗生素,被认为是第二代头孢菌素。它显示出对β-内酰胺酶的耐药性,并用于治疗由革兰氏阳性和革兰氏阴性细菌引起的广谱细菌感染,如支气管炎、咽炎、脑膜炎和尿路感染等。头孢西丁用于静脉和肌肉注射。已发现它对拟杆菌具有活性,可用于治疗混合好氧-厌氧感染。
应用
分析标准品可用于:
- 在纯剂型和药物剂型的碱性降解产物环境下,使用四种稳定性指示分光光度法测定头孢西丁钠
- 通过高效液相色谱法(HPLC)分离和测定商业药品中的头孢西丁钠
其他说明
有关合适的仪器技术的更多信息,请参阅产品′的检验报告。想要获得更多支持,请联系技术服务部。
警示用语:
Warning
危险声明
危险分类
Skin Sens. 1B
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
监管及禁止进口产品
Antibiotic and chemotherapy e-book, 14(3), 257-266 (2010)
Methicillin-resistant Staphylococcus aureus screening by online immunometric monitoring of bacterial growth under selective pressure.
Antimicrobial Agents and Chemotherapy, 53(12), 5088-5094 (2009)
Spectrofluorimetric analysis of cefoxitin in pharmaceutical dosage
Talanta, 41(4), 557-563 (1994)
Journal of clinical microbiology, 50(5), 1779-1782 (2012-02-18)
Cefoxitin-resistant Escherichia coli (n = 109) and Klebsiella pneumoniae (n = 16) isolates collected from patients in India in 2009 to 2010 were screened for bla(ampC) families and mobilizing elements (ISEcp1, IS26, ISCR1, and sul-1-type class 1 integrons) and their
The Indian journal of medical research, 135, 114-119 (2012-03-03)
Plasmid mediated AmpC β-lactamase (PMABL) resistance in Escherichia coli and Klebsiella spp. is an emerging problem worldwide. Phenotypic methods are commonly used for detection of PMABL production in Gram-negative isolates, but molecular data about the prevalence of plasmid-mediated AmpC-type resistance
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