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安全信息

C2800000

Cortisone acetate

European Pharmacopoeia (EP) Reference Standard

别名:

Cortisone 21-acetate, 17α,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate, 21-Acetoxy-4-pregnen-17α-ol-3,11,20-trione, 4-Pregnene-17α,21-diol-3,11,20-trione 21-acetate

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1 ML
CN¥1,681.42

CN¥1,681.42

预计发货时间June 25, 2025详情

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1 ML
CN¥1,681.42

About This Item

经验公式（希尔记法）:
C23H30O6
CAS号:
50-04-4
分子量:
402.48
Beilstein:
2067543
MDL编号:
MFCD00003609
UNSPSC代码:
41116107
PubChem化学物质编号:
329774751
NACRES:
NA.24

CN¥1,681.42

预计发货时间June 25, 2025详情

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等级

pharmaceutical primary standard

API类

cortisone

制造商/商品名称

EDQM

mp

237-240 °C (lit.)

应用

pharmaceutical (small molecule)

包装形式

neat

SMILES字符串

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])C(=O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O

InChI

1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1

InChI key

ITRJWOMZKQRYTA-RFZYENFJSA-N

基因信息

human ... NR3C1(2908)

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AB1837PMAB1021T6817
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AB2148P

Anti-Tumor Necrosis Factor-α Antibody

抗肿瘤坏死因子-α 抗体。 Chemicon®, from rabbit

AB1837P

抗肿瘤坏死因子-α 抗体。

Anti-Tumor Necrosis Factor-α Antibody, clone 2C8 clone 2C8, Chemicon®, from mouse

MAB1021

Anti-Tumor Necrosis Factor-α Antibody, clone 2C8

Monoclonal Anti-Tumor Necrosis Factor-α antibody produced in mouse clone 28401, purified immunoglobulin, lyophilized powder

T6817

Monoclonal Anti-Tumor Necrosis Factor-α antibody produced in mouse

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

biological source

rabbit

biological source

rabbit

biological source

mouse

biological source

mouse

species reactivity

mouse

species reactivity

rat

species reactivity

human

species reactivity

human

clone

polyclonal

clone

polyclonal

clone

2C8, monoclonal

clone

28401, monoclonal

UniProt accession no.

P06804

UniProt accession no.

P01375

UniProt accession no.

P01375

UniProt accession no.

P01375

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Cortisone acetate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Health hazard
GHS08

警示用语：

Warning

危险声明

H361d

危险分类

Repr. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yin-Hu Ma et al.
The Journal of steroid biochemistry and molecular biology, 117(4-5), 146-151 (2009-09-12)
An intensive and systematic investigation had been carried out on the Delta(1)-dehydrogenation of cortisone acetate (CA) to prednisone acetate (PA) by Arthrobacter simplex TCCC 11037 in the presence of native and modified beta-cyclodextrins (beta-CDs). The biotransformation was improved through the
K Mai et al.
Clinical endocrinology, 63(4), 442-449 (2005-09-27)
Free fatty acids (FFAs) induce hepatic insulin resistance and enhance hepatic gluconeogenesis. Glucocorticoids (GCs) also stimulate hepatic gluconeogenesis. The aim of this study was to investigate whether the FFA-induced hepatic insulin resistance is mediated by increased activity of hepatic 11beta-hydroxysteroid
Wiebke Arlt et al.
Clinical endocrinology, 64(4), 384-389 (2006-04-06)
Evaluation of glucocorticoid replacement quality in adrenal insufficiency (AI) relies primarily on clinical judgement and thus largely depends on the physician's expertise. It is a matter of debate whether cortisol day curves are of value in assessing glucocorticoid replacement quality.
L Barbetta et al.
Journal of endocrinological investigation, 28(7), 632-637 (2005-10-13)
Since the optimal glucocorticoid replacement needs to avoid over and under treatment, the adequacy of different daily cortisone acetate (CA) doses was assessed in 34 patients with primary and central hypoadrenalism. The conventional twice CA 37.5 mg/day dose was administered
Silvia Slesiona et al.
The Journal of infectious diseases, 205(8), 1268-1277 (2012-03-23)
Aspergillus terreus is emerging as a causative agent of life-threatening invasive aspergillosis. Prognosis for affected patients is often worse than for A. fumigatus infections. To study A. terreus-mediated disease, we developed 3 infection models. In embryonated hen's eggs and leucopenic
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