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经验公式(希尔记法):
C18H33ClN2O5S · HCl
化学文摘社编号:
分子量:
461.44
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4070786
产品名称
克林霉素 盐酸盐, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1
SMILES string
Cl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@H](C)Cl)C2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O
InChI key
AUODDLQVRAJAJM-XJQDNNTCSA-N
grade
pharmaceutical primary standard
API family
clindamycin
manufacturer/tradename
EDQM
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Biochem/physiol Actions
克林霉素是一种由林可霉素制备的半合成林可酰胺类抗生素。 它通过与 50S 核糖体亚基的 23S rRNA 组分的氢键相互作用,抑制细菌蛋白质合成,从而诱导肽基-t-RNA 复合物的解离。它具有抗革兰氏阳性球菌的抗菌活性,以及抗弓形虫的抗原虫活性。
Other Notes
林可酰胺类的抗菌和抗原生动物抗生素。
Sales restrictions may apply.
Application
Clindamycin hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Lact. - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
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