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关于此项目
经验公式（希尔记法）:
C12H17NO2 · C2H7NO
化学文摘社编号:
分子量:
268.35
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C12H17NO2.C2H7NO/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10;3-1-2-4/h7-8,10,15H,2-6H2,1H3;4H,1-3H2
SMILES string
NCCO.CC1=CC(=O)N(O)C(=C1)C2CCCCC2
InChI key
MBRHNTMUYWQHMR-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
ciclopirox
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Ciclopirox olamine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Sae Hee Ko et al.
PloS one, 6(11), e27844-e27844 (2011-11-30)
Diabetic wounds remain a major medical challenge with often disappointing outcomes despite the best available care. An impaired response to tissue hypoxia and insufficient angiogenesis are major factors responsible for poor healing in diabetic wounds. Here we show that the
Fabiana Silva Felix et al.
Electrophoresis, 32(8), 900-905 (2011-03-12)
This paper describes the determination of ciclopirox olamine in pharmaceutical formulations using capillary electrophoresis with capacitively coupled contactless conductivity detection. In an alkaline medium, ciclopirox olamine is converted into an anionic species and its detection is possible in capillary electrophoresis
Mark D Minden et al.
American journal of hematology, 89(4), 363-368 (2013-11-26)
The antimycotic ciclopirox olamine is an intracellular iron chelator that has anticancer activity in vitro and in vivo. We developed an oral formulation of ciclopirox olamine and conducted the first-in-human phase I study of this drug in patients with relapsed
Siyuan Song et al.
Cancer research, 71(24), 7628-7639 (2011-10-20)
Excessive signaling from the Wnt pathway is associated with numerous human cancers. Using a high throughput screen designed to detect inhibitors of Wnt/β-catenin signaling, we identified a series of acyl hydrazones that act downstream of the β-catenin destruction complex to
Aditya K Gupta et al.
The Journal of dermatological treatment, 25(3), 256-259 (2012-05-30)
Computerized nail planimetry is an objective means of accurately assessing affected nail areas, versus the standard visual estimation method. However, no published comparison of visual assessment with planimetry is currently available on onychomycosis to support this recommendation. This article evaluates
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