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Merck
CN

C2158000

胆酸

European Pharmacopoeia (EP) Reference Standard

别名:

3α,7α,12α-三羟基-5β-胆烷酸, 胆烷酸

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About This Item

经验公式(希尔记法):
C24H40O5
CAS号:
分子量:
408.57
Beilstein:
2822009
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

Agency

EP Reference Standard

API类

cholic acid

制造商/商品名称

EDQM

mp

200-201 °C (lit.)

应用

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

包装形式

neat

SMILES字符串

[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(O)=O

InChI

1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1

InChI key

BHQCQFFYRZLCQQ-OELDTZBJSA-N

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一般描述

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。 如需进一步信息和支持,请访问现行药典网站。

应用

用于提取膜蛋白的非变性离子洗涤剂。

生化/生理作用

胆汁酸

包装

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

其他说明

可能适用相应的销售限制。

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Nevzat Kazgan et al.
Gastroenterology, 146(4), 1006-1016 (2014-01-07)
Sirtuin 1 (SIRT1), the most conserved mammalian oxidized nicotinamide adenine dinucleotide-dependent protein deacetylase, is an important metabolic sensor in many tissues. However, little is known about its role in the small intestine, which absorbs and senses nutrients. We investigated the
Zheng Pan et al.
Carbohydrate polymers, 94(1), 394-399 (2013-04-03)
Self-assembled amphiphilic N-(2,3-dihydroxypropyl)-chitosan-cholic acid (DHP-CS-CHO) micelle was prepared as a carrier for paclitaxel. DHP-CS-CHO was synthesized by grafted small molecules cholic acid and glycidol onto primary amine group of chitosan, respectively. The DHP-CS-CHO formed uniform micelles (size=212.4±3.1 nm) with a
Sylwia Mildner-Szkudlarz et al.
Journal of the science of food and agriculture, 93(13), 3271-3278 (2013-04-16)
New breads fortified with two different forms of grape by-products, namely dried powdered skins (PGP) and freeze-dried extract therefrom (EGP), were characterised and their protective effect against hypercholesterolaemia in rats was studied. The phenolic compound profiles of supplemented breads were
Yu Shao et al.
ACS applied materials & interfaces, 6(13), 10381-10392 (2014-06-13)
To develop a feasible and efficient nanocarrier for potential clinical application, a series of photo and redox dual responsive reversibly cross-linked micelles have been developed for the targeted anticancer drug delivery. The nanocarrier can be cross-linked efficiently via a clean
Chiara Gabbi et al.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 44(12), 1018-1026 (2012-08-14)
Non-alcoholic fatty liver disease, one of the most prevalent liver disorders in Western countries, is characterized by hepatic accumulation of triglycerides. Bile acids have long been known to affect triglyceride homeostasis through a not completely understood mechanism. To analyse the

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