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Merck
CN

C0982

Sigma-Aldrich

氯丙嗪 盐酸盐

meets USP testing specifications

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别名:
2-氯-10-(3-二甲氨基丙基)吩噻嗪 盐酸盐, CPZ, 氯普马嗪
经验公式(希尔记法):
C17H19ClN2S · HCl
CAS号:
分子量:
355.33
Beilstein:
3779989
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.21

生物来源

synthetic (organic)

质量水平

Agency

USP/NF
meets USP testing specifications

检测方案

98.0-101.5% dry basis

形式

solid

mp

194-196  °C

溶解性

water: soluble 50 g/L

应用

pharmaceutical (small molecule)

储存温度

room temp

SMILES字符串

Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13

InChI

1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

InChI key

FBSMERQALIEGJT-UHFFFAOYSA-N

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应用

在血红蛋白和过氧化物酶的微量测定中替代联苯胺、邻联茴香胺和邻联甲苯胺。

生化/生理作用

吩噻嗪类抗精神病药;D2 多巴胺受体拮抗剂,H1 组胺受体拮抗剂;抑制钙调蛋白依赖性环核苷酸磷酸二酯酶和一氧化氮合成酶的活化。
氯丙嗪表现出对白血病细胞的细胞毒性和抗增殖活性,但是不会影响正常淋巴细胞的活力。

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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