C0415
环吡司胺
analytical standard
别名:
6-环己基-1-羟基-4-甲基-2(1H)-吡啶酮 乙醇胺盐
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关于此项目
经验公式（希尔记法）:
C12H17NO2 · C2H7NO
化学文摘社编号:
分子量:
268.35
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
255-464-9
MDL number:
InChI key
MBRHNTMUYWQHMR-UHFFFAOYSA-N
InChI
1S/C12H17NO2.C2H7NO/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10;3-1-2-4/h7-8,10,15H,2-6H2,1H3;4H,1-3H2
SMILES string
NCCO.CC1=CC(=O)N(O)C(=C1)C2CCCCC2
grade
analytical standard
assay
≥97%
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
D Monti et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 27(2), e153-e158 (2012-03-28)
In a previous study a new hydrosoluble nail lacquer (P-3051) containing 8% ciclopirox (CPX) showed higher nail penetration compared to a water-insoluble 5% amorolfine (MRF) lacquer. To our knowledge, in vivo human data on a similar topic are not available.
Ciclopirox olamine 1% cream. A preliminary review of its antimicrobial activity and therapeutic use.
S G Jue et al.
Drugs, 29(4), 330-341 (1985-04-01)
Ciclopirox olamine is a substituted pyridone antimycotic, unrelated to the imidazole derivatives, with activity against a broad spectrum of dermatophytes, yeasts, actinomycetes, molds, other fungi, and a variety of Gram-positive and Gram-negative bacteria. The efficacy of ciclopirox olamine cream has
D Monti et al.
The British journal of dermatology, 165(1), 99-105 (2011-03-18)
Topical therapy has recently been proposed for treating onychomycosis and other nail disturbances. However, the clinical outcome may be limited by the difficulty of active ingredients effectively penetrating the nail plate. Bovine hoof membranes have been widely used to predict
Tsuyoshi Shimamura et al.
Antimicrobial agents and chemotherapy, 55(7), 3150-3155 (2011-05-11)
We developed a novel model of onychomycosis in which we observed fungi in the deep layer of the nail, and we used the model to evaluate the efficacy of two topical antifungal drugs. To establish an experimental, in vivo model
Luis Nogueiras-Nieto et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 83(3), 370-377 (2012-12-04)
This work investigated the use of in situ gelling hydrogels based on polypseudorotaxanes of Pluronic F-127 and partially methylated β-cyclodextrin as aqueous nail lacquers. N-acetylcysteine and urea were incorporated as penetration enhancers. The formulations were tested for their ability to
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