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安全信息

BP793

布地奈德

British Pharmacopoeia (BP) Reference Standard

别名:

16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione

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About This Item

经验公式（希尔记法）:
C25H34O6
CAS号:
51333-22-3
分子量:
430.53
MDL编号:
MFCD00083259
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

budesonide

表单

solid

保质期

limited shelf life, expiry date on the label

制造商/商品名称

BP

应用

pharmaceutical
pharmaceutical small molecule

包装形式

neat

SMILES字符串

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H]5OC(CCC)O[C@@]45C(=O)CO

InChI

1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1

InChI key

VOVIALXJUBGFJZ-KWVAZRHASA-N

基因信息

human ... NR3C1(2908)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Budesonide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Budesonide Aqueous Nasal Spray
  • Budesonide Inhalation Powder, pre-metered
  • Budesonide Inhalation Powder
  • Budesonide Pressurised Inhalation
  • Budesonide Nebuliser Suspension

    • 生化/生理作用

    Budesonide is a second generation glucocorticoid with low systemic absorption. It is used as an anti-inflammatory agent in the treatment of asthma, rhinitis, and inflammatory bowel disease. It inhibits the expression of chemokine mRNA and production of eotaxin and RANTES protein in primary human bronchial epithelial cells. Budesonide is currently in clinical trials for the prevention of lung cancer. It shows inhibitory effects on benzo[a]pyrene-induced carcinogenesis of the lung in mice.

    包装

    Unit quantity: 110 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    其他说明

    Sales restrictions may apply.

    相关产品

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    Y0001148

    系统适用性试验用布地奈德, European Pharmacopoeia (EP) Reference Standard

    1078201

    布地奈德, United States Pharmacopeia (USP) Reference Standard

    1078289

    Budesonide Related Compound L, United States Pharmacopeia (USP) Reference Standard

    1078267

    Budesonide Related Compound G, United States Pharmacopeia (USP) Reference Standard

    1078245

    Budesonide Related Compound E, United States Pharmacopeia (USP) Reference Standard

    PHR1823

    布地奈德相关化合物L, Pharmaceutical Secondary Standard; Certified Reference Material

    PHR1822

    Budesonide Related Compound G, Pharmaceutical Secondary Standard; Certified Reference Material

    BP894

    布地奈德杂质标准品, British Pharmacopoeia (BP) Reference Standard

    象形图

    Health hazardExclamation mark
    GHS08,GHS07

    警示用语：

    Danger

    危险分类

    Acute Tox. 4 Oral - Aquatic Chronic 3 - Repr. 2 - Skin Sens. 1 - STOT RE 1 Inhalation

    靶器官

    Adrenal gland

    储存分类代码

    6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    WGK

    WGK 3

    闪点(°F)

    Not applicable

    闪点(°C)

    Not applicable

    法规信息

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    分析证书(COA)

    Lot/Batch Number

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