等级
pharmaceutical primary standard
API类
hydrocortisone
形式
solid
保质期
limited shelf life, expiry date on the label
制造商/商品名称
BP
mp
211-214 °C (lit.)
应用
pharmaceutical
pharmaceutical small molecule
格式
neat
SMILES字符串
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
InChI
1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
InChI key
JYGXADMDTFJGBT-VWUMJDOOSA-N
基因信息
human ... NR3C1(2908)
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一般描述
本产品由现行药典发布和说明。随附的本产品的所有支持信息，包括SDS和任何产品信息彩页，均遵照现行药典许可而编制和发布。
有关更多信息和支持，请参见现行药典网站。
有关更多信息和支持，请参见现行药典网站。
应用
Hydrocortisone BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.
Also used in monographs such as:Tretinoin, Hydrocortisone and Hydroquinone Cream Miconazole and Hydrocortisone Acetate Cream Hydrocortisone Sodium Succinate Injection Prednisolone Tablets Miconazole and Hydrocortisone Cream Miconazole and Hydrocortisone Ointment Hydrocortisone and Neomycin Cream Hydrocortisone and Clioquinol Ointment Hydrocortisone Sodium Phosphate Oral Solution Prednisolone Gastro-resistant Tablets Hydrocortisone Sodium Phosphate Hydrocortisone Sodium Phosphate Injection Hydrocortisone and Clioquinol Cream Methylprednisolone Tablets Hydrocortisone Acetate Oral Suspension Hydrocortisone Cream Hydrocortisone Oromucosal Tablets
Also used in monographs such as:
生化/生理作用
肾上腺皮质分泌的原始糖皮质激素。它的抗炎效力是皮质酮的三倍，但 Na2+ 保留效力要低得多。
其他说明
可能适用相应的销售限制。
相关产品
产品编号
说明
价格
警示用语：
Danger
危险声明
危险分类
Repr. 1A - STOT RE 2
靶器官
Adrenal gland,Bone marrow
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
Florian Hardeveld et al.
Psychoneuroendocrinology, 50, 62-71 (2014-09-03)
Although HPA-axis activity has been studied extensively in relation to depression, there is no consensus whether HPA-axis parameters predicts major depressive disorder (MDD) recurrence. We investigated whether HPA-axis parameters (cortisol awakening response (CAR), the dexamethasone suppression test (DST) and evening
Lorenz Goette et al.
Psychoneuroendocrinology, 54, 115-123 (2015-02-24)
Social competition is a fundamental mechanism of evolution and plays a central role in structuring individual interactions and communities. Little is known about the factors that affect individuals' competitive success, particularly in humans. Key factors might include stress, a major
Karin E Koopman et al.
Hepatology (Baltimore, Md.), 60(2), 545-553 (2014-03-29)
American children consume up to 27% of calories from high-fat and high-sugar snacks. Both sugar and fat consumption have been implicated as a cause of hepatic steatosis and obesity but the effect of meal pattern is largely understudied. We hypothesized
Marianne Oksnes et al.
The Journal of clinical endocrinology and metabolism, 99(5), 1665-1674 (2014-02-13)
Conventional glucocorticoid replacement therapy fails to mimic the physiological cortisol rhythm, which may have implications for morbidity and mortality in patients with Addison's disease. The objective of the study was to compare the effects of continuous sc hydrocortisone infusion (CSHI)
Mario Cioce et al.
Oncotarget, 5(12), 4129-4143 (2014-07-02)
Metabolic remodeling is a hallmark of cancer progression and may affect tumor chemoresistance. Here we investigated by 1H-NMR/PCA analysis the metabolic profile of chemoresistant breast cancer cell subpopulations (ALDHbright cells) and their response to metformin, a promising anticancer metabolic modulator.
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