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Merck
CN

BP423

维生素 K 1

British Pharmacopoeia (BP) Reference Standard

别名:

2-甲基-3-植基-1,4-萘醌, 叶绿醌, 植物甲萘醌, 维生素 K1(20)

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About This Item

经验公式(希尔记法):
C31H46O2
CAS号:
分子量:
450.70
Beilstein:
2568816
EC 号:
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

phytomenadione

形式

viscous liquid (Clear)

保质期

limited shelf life, expiry date on the label

制造商/商品名称

BP

折射率

n20/D 1.527 (lit.)

mp

−20 °C (lit.)

密度

0.984 g/mL at 25 °C (lit.)

应用

pharmaceutical
pharmaceutical small molecule

格式

neat

储存温度

2-8°C

SMILES字符串

O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O

InChI

1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1

InChI key

MBWXNTAXLNYFJB-NKFFZRIASA-N

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一般描述

Phytomenadione is a synthetic lipid-soluble forms of vitamin K1, and works as an essential cofactor for the post-translational γ-carboxyglutamate (Gla) residues in several blood coagulation factors. It is used to treat coagulopathies caused by anticoagulant toxicosis.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Phytomenadione BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Phytomenadione Injection
  • Phytomenadione Tablets
  • 包装

    Unit quantity: 0.25 mL. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    其他说明

    Sales restrictions may apply.

    储存分类代码

    10 - Combustible liquids

    WGK

    WGK 1

    闪点(°F)

    Not applicable

    闪点(°C)

    Not applicable


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    分析证书(COA)

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    访问文档库

    Papich GM, et al. et al.
    Saunders Handbook of Veterinary Drugs, (4), 637-638 (2016)
    HPLC-APCI-MS for the determination of vitamin K1 in human plasma: method and clinical application
    Song Q, et al.
    Journal of Chromatography. B, Biomedical Sciences and Applications, 875(2), 541-545 (2008)
    Rapid HPLC assay for the assessment of vitamin K1, A, E and beta-carotene status in children (7-19 years)
    Jakob E and Elmadfa I
    Internat. J. Vit. Nutr. Res., 65(1), 31-35 (1995)

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