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BP253

（±）-咪康唑硝酸盐

Name: （±）-咪康唑 硝酸盐
Brand: SIAL

British Pharmacopoeia (BP) Reference Standard

别名:

1-（2,4-二氯-β-[（2,4-二氯苄基）氧] 苯乙基 ] 咪唑

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About This Item

经验公式（希尔记法）:

C₁₈H₁₄Cl₄N₂O · HNO₃

CAS号:

22832-87-7

分子量:

479.14

EC 号:

245-256-6

MDL编号:

MFCD00058161

UNSPSC代码:

41116107

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

miconazole

形式

solid

保质期

limited shelf life, expiry date on the label

制造商/商品名称

应用

pharmaceutical
pharmaceutical small molecule

格式

neat

储存温度

2-8°C

SMILES字符串

ClC1=CC(Cl)=CC=C1C(OCC2=CC=C(Cl)C=C2Cl)CN3C=CN=C3.[O-][N+](O)=O

InChI

1S/C18H14Cl4N2O.HNO3/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22;2-1(3)4/h1-8,11,18H,9-10H2;(H,2,3,4)

InChI key

MCCACAIVAXEFAL-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Miconazole nitrate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Miconazole and Hydrocortisone Acetate Cream

Miconazole and Hydrocortisone Cream

Miconazole and Hydrocortisone Ointment

Miconazole Eye Drops

Miconazole Oromucosal Gel

Miconazole Cream

生化/生理作用

咪康唑与 14-α 相互作用脱甲基酶，一种麦角固醇生物合成所必需的细胞色素 P-450 酶。麦角固醇的抑制导致细胞通透性增加引起细胞内容物渗漏。咪康唑还可能抑制内源性呼吸，与细胞膜中的磷脂相互作用，抑制酵母菌转化为菌丝形式，抑制嘌呤摄取，干扰甘油三酯和磷脂的生物合成。

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

象形图

GHS07

警示用语：

Warning

危险声明

H302,H317

预防措施声明

P280 - P301 + P312 + P330

危险分类

Acute Tox. 4 Oral - Skin Sens. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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分析证书(COA)

Lot/Batch Number

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（±）-咪康唑 硝酸盐