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Merck
CN

BP1094

环磷酰胺

British Pharmacopoeia (BP) Reference Standard

别名:

环磷酰胺 一水合物, 2-[双(2-氯乙基)氨基]四氢-2H-1,3,2-噁磷-2-氧化物, Cytoxan

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关于此项目

经验公式(希尔记法):
C7H15Cl2N2O2P · H2O
化学文摘社编号:
分子量:
279.10
NACRES:
NA.24
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
4678992
MDL number:
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产品名称

环磷酰胺, British Pharmacopoeia (BP) Reference Standard

SMILES string

[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1

InChI key

PWOQRKCAHTVFLB-UHFFFAOYSA-N

InChI

1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

grade

pharmaceutical primary standard

API family

cyclophosphamide

form

crystalline

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

mp

49-51 °C (lit.)

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

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Biochem/physiol Actions

广泛用于癌症化疗的细胞毒性氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。
环磷酰胺是一种广泛用于癌症化疗的具有细胞毒性的氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。其临床活性与乙醛脱氢酶 1 (ALDH1) 的活性降低相关。

Application

Cyclophosphamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Cyclophosphamide Oral Solution
  • General description

    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

    Other Notes

    Sales restrictions may apply.
    Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    pictograms

    Skull and crossbonesHealth hazard

    signalword

    Danger

    Hazard Classifications

    Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A

    存储类别

    6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    wgk

    WGK 3

    flash_point_f

    235.4 °F - closed cup

    flash_point_c

    113 °C - closed cup


    历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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