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Merck
CN

BCR306

1-硝基萘

BCR®, certified reference material

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经验公式(希尔记法):
C10H7NO2
化学文摘社编号:
分子量:
173.17
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
201-684-5
Beilstein/REAXYS Number:
1867714
MDL number:
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InChI key

RJKGJBPXVHTNJL-UHFFFAOYSA-N

InChI

1S/C10H7NO2/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H

SMILES string

[O-][N+](=O)c1cccc2ccccc12

grade

certified reference material

agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

bp

304 °C (lit.)

density

1.223 g/mL at 25 °C (lit.)

format

neat

storage temp.

2-8°C

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General description

1-Nitronaphthalene, belonging to the class of nitrated-polycyclic aromatic hydrocarbons, is persistent in the environment. It is produced from direct sources such as diesel, gasoline exhaust and gas-phase reactions of polycyclic aromatic hydrocarbons (PAHs) with oxides of nitrogen.

Analysis Note

For more information please see:
BCR306

Legal Information

BCR is a registered trademark of European Commission

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Flam. Sol. 2

存储类别

4.1B - Flammable solid hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品
此项目有

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Determination and comparison of nitrated-polycyclic aromatic hydrocarbons measured in air and diesel particulate reference materials
Bamford AH, et al.
Chemosphere, 50 (5), 575-587 (2003)
Ching Yu Lin et al.
Proteomics, 6(3), 972-982 (2006-02-03)
Naphthalene and 1-nitronaphthalene are ambient air pollutants, which undergo P450-dependent bioactivation in the lung. Reactive metabolites of naphthalene and 1-nitronaphthalene covalently bind to proteins, and the formation of covalent adducts correlates with airway epithelial cell injury in rodent models. These
Kara R Schmelzer et al.
Environmental health perspectives, 114(9), 1354-1360 (2006-09-13)
Ambient air is polluted with a mixture of pulmonary toxicants. Previous studies indicate that prior exposure to atmospheric oxidant pollutants such as ozone may significantly alter the response to other pollutants, such as 1-nitronaphthalene (1-NN) . 1-NN, a component of
Gregory L Baker et al.
Toxicological sciences : an official journal of the Society of Toxicology, 77(1), 135-141 (2003-11-06)
The mechanisms of toxicant-mediated lung injury and repair are influenced by the considerable spatial heterogeneity that exists within the conducting airways of the lungs. As a result of this heterogeneity, significant differences and similarities in gene expression are observed throughout
R C Paige et al.
The Journal of pharmacology and experimental therapeutics, 295(3), 934-941 (2000-11-18)
To test whether exposure to ozone alters pulmonary cytochrome P450 monooxygenase-mediated metabolism of xenobiotics, rates of 1-nitronaphthalene (1-NN) metabolism were measured in microsomes prepared from trachea, intrapulmonary airways, and distal lung of rats exposed to filtered air (FA) or ozone

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