InChI
1S/C17H11N/c1-3-7-15-12(5-1)9-10-14-11-13-6-2-4-8-16(13)18-17(14)15/h1-11H
SMILES string
c1ccc2nc3c(ccc4ccccc34)cc2c1
InChI key
OAPPEBNXKAKQGS-UHFFFAOYSA-N
grade
certified reference material
agency
BCR®
manufacturer/tradename
JRC
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
format
neat
storage temp.
2-8°C
Analysis Note
For more information please see:
BCR158
BCR158
Legal Information
BCR is a registered trademark of European Commission
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
H Sakagami et al.
Anticancer research, 15(6B), 2533-2540 (1995-11-01)
A series of phenothiazine, benzo[a]phenothiazine and benz[c]acridine derivatives were compared for their ability to induce nucleosome-sized DNA fragmentation (a biochemical hallmark of apoptosis), using agarose gel electrophoresis and a fluorescence activated cell sorter. Significant DNA fragmentation-inducing activity was detected in
T Kurihara et al.
Anticancer research, 18(1A), 429-432 (1998-05-06)
On the calculated pi-spin density (rho pi) of benz[c]acridines [1-12], benz[c]acridines [2,8-12] with alternately value of pi-spin density (rho pi) on angular ring, large negative pi-spin density at C-1 and C-3 positions and large positive pi-spin density at C-2 and
K Kamata et al.
Anticancer research, 9(3), 579-582 (1989-05-01)
Raman spectra of methyl substituted benz[c]acridines (BAc) in the solid state were recorded. Their assignments were proposed for the frequencies of Raman spectra observed. The purpose of this work was to elucidate the mechanisms of interaction between BAc and DNA
M Tanaka et al.
Anticancer research, 16(5A), 2837-2841 (1996-09-01)
The mutagenicity of eleven methylbenz[c]acridines (methyl-B[c]ACRs) was examined by the direct Ames' Salmonella mutagenicity assay on the standard tester strains of TA97a, TA98, TA100 and TA102, each of which is specific to a certain type of mutation. The Benz[c]acridines (B[c]ACRs)
T Kurihara et al.
Anticancer research, 16(5A), 2757-2765 (1996-09-01)
In order to clarify the effects of methyl substitution on the carcinogenic activity, each resonance energy (RE) of benz[c]acridines, benzo[a]phenothiazines, chrysene, and their methyl derivatives was calculated by Aihara's TRE theory. Some correlations seem to exist between the values of
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