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Merck
CN

BCR050

苯并[e]芘

BCR®, certified reference material

别名:

1,2-苯并芘, 4,5-苯并芘

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关于此项目

经验公式(希尔记法):
C20H12
化学文摘社编号:
分子量:
252.31
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
205-892-7
Beilstein/REAXYS Number:
1911334
MDL number:
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InChI key

TXVHTIQJNYSSKO-UHFFFAOYSA-N

InChI

1S/C20H12/c1-2-8-16-15(7-1)17-9-3-5-13-11-12-14-6-4-10-18(16)20(14)19(13)17/h1-12H

SMILES string

c1ccc2c(c1)c3cccc4ccc5cccc2c5c34

grade

certified reference material

agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

177-180 °C (lit.)

format

neat

storage temp.

2-8°C

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Analysis Note

For more information please see:
BCR050

Legal Information

BCR is a registered trademark of European Commission

pictograms

Health hazardEnvironment

signalword

Danger

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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D S Vienneau et al.
Cancer research, 55(5), 1045-1051 (1995-03-01)
UDP-glucuronosyltransferases (UGTs) are cytoprotective and may also be genoprotective. Since over 10% of the population have hereditary deficiencies in UGTs, this family of enzymes could constitute an important determinant of susceptibility to chemical carcinogenesis, teratogenesis, and neurodegeneration. Fibroblasts contain Phase
D F Lewis et al.
Toxicology letters, 71(3), 235-243 (1994-05-01)
The present studies were undertaken to provide a rationale for the observation that benzo(a)pyrene and 2-acetylaminofluorene induce the hepatic CYP1A1 protein, whereas their non-carcinogenic isomers benzo(e)pyrene and 4-acetylaminofluorene are, at best, relatively very weak inducers. Using amino acid sequence alignment
Narumi Sugihara et al.
Toxicology in vitro : an international journal published in association with BIBRA, 21(5), 827-834 (2007-04-06)
The previous studies from our laboratory reported that benzo(a)pyrene (Bap) influenced efflux transport of rhodamine 123 (Rho-123) by induction of P-glycoprotein (P-gp) in Caco-2 cells. The present study investigated whether induction of P-gp and the enhanced efflux transport of Rho-123
Saffar Mansoor et al.
Investigative ophthalmology & visual science, 51(5), 2601-2607 (2009-12-05)
To study the inhibitory effects of some agents or drugs (inhibitors) on benzo(e)pyrene (B(e)P)-induced cell death and apoptosis on human retinal pigment epithelial (ARPE-19) cells in vitro. ARPE-19 cells were pretreated with varying concentrations of different classes of inhibitors (calpain
A Jayaprakash Patil et al.
Current eye research, 34(8), 672-682 (2009-11-11)
To study the effects of benzo(e)pyrene (B(e)P), a toxic component of cigarette smoke, on retinal neurosensory (R28) cells and human microvascular endothelial cells (HMVEC). R28 cells and HMVEC were treated for 24 hours with 1000, 400, 200, and 100 micro

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