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Merck
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安全信息

B8800

Sigma-Aldrich

杆菌肽 锌盐

from Bacillus licheniformis, meets USP testing specifications

别名:

杆菌肽锌

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About This Item

经验公式（希尔记法）:
C66H101N17O16SZn
CAS号:
1405-89-6
分子量:
1486.07
EC 号:
215-787-8
MDL编号:
MFCD00130598
UNSPSC代码:
41116107
PubChem化学物质编号:
24892095
NACRES:
NA.76

生物来源

Bacillus licheniformis

质量水平

200

Agency

USP/NF
meets USP testing specifications

表单

powder

mp

250 °C (dec.) (lit.)

抗生素抗菌谱

Gram-positive bacteria

应用

pharmaceutical (small molecule)

作用机制

cell wall synthesis | interferes

储存温度

2-8°C

SMILES字符串

[Zn++].CCC(C)C(N)C1=NCC(S1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC([O-])=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC([O-])=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC

InChI

1S/C66H103N17O16S.Zn/c1-9-35(6)52(69)66-72-32-48(100-66)63(97)80-43(26-34(4)5)59(93)75-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)76-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-73-39)77-60(94)44(27-38-18-13-12-14-19-38)81-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)74-56(40)90;/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,73)(H,71,89)(H,74,90)(H,75,93)(H,76,98)(H,77,94)(H,78,96)(H,79,95)(H,80,97)(H,81,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88);/q;+2/p-2/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-;/m0./s1

InChI key

NKULICGUDKGGRL-FCHFGNCGSA-L

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一般描述

Chemical structure: peptide

应用

Bacitracin is used to study the disruption of bacterial cell wall synthesis at the level of peptidoglycan biosynthesis and isoprenyl metabolism. Used to study the biosynthesis of sterols and squalene.

其他说明

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000166468
0000166468
0000117418
0000113945
0000090844

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Vanina Dengler et al.
FEMS microbiology letters, 333(2), 109-120 (2012-05-30)
The Staphylococcus aureus cell wall stress stimulon (CWSS) is activated by cell envelope-targeting antibiotics or depletion of essential cell wall biosynthesis enzymes. The functionally uncharacterized S. aureus LytR-CpsA-Psr (LCP) proteins, MsrR, SA0908 and SA2103, all belong to the CWSS. Although not
Shanna Spring et al.
Dermatitis : contact, atopic, occupational, drug, 23(5), 210-213 (2012-09-27)
Topical medicaments are a common cause of allergic contact dermatitis. This study will evaluate the prevalence of contact allergy to a wide array of topical medicaments at the Ottawa Patch Test Clinic. The objectives of this study are to report
Audrey Charlebois et al.
PloS one, 7(9), e44449-e44449 (2012-09-13)
Phenotypic bacitracin resistance has been reported in Clostridium perfringens. However, the genes responsible for the resistance have not yet been characterized. Ninety-nine C. perfringens isolates recovered from broilers and turkeys were tested for phenotypic bacitracin resistance. Bacitracin MIC(90) (>256 µg/ml)
Marta Estela Saravia et al.
Archives of oral biology, 58(3), 311-316 (2012-11-15)
The recovery of mutans streptococci in saliva and dental biofilm samples depends, in part, on the culture medium used. In this study, we compared (i) the culture media Sucrose-Bacitracin agar (SB-20), Modified SB-20 (SB-20M) and Mitis Salivarius Bacitracin agar (MSB)
Alina Olender et al.
Medycyna doswiadczalna i mikrobiologia, 64(1), 1-10 (2012-07-20)
The genus Streptococcus comprises a number of species characterized by a differential pathogenic potential. These bacteria can be considered as members of microbial physiological flora but they can also cause mild infections or severe, life threatening conditions. The majority of
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