所有图片(1)
About This Item
经验公式（希尔记法）:
C17H25NO4 · HCl
CAS号:
分子量:
343.85
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
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等级
analytical standard
质量水平
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
包装形式
neat
SMILES字符串
Cl.COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1
InChI
1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H
InChI key
ZDPACSAHMZADFZ-UHFFFAOYSA-N
基因信息
human ... EBP(10682)
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一般描述
Buflomedil hydrochloride is a vasoactive agent. Its mode of action involves increasing the peripheral and cerebral blood flow in ischaemic tissues of patients, who are mostly affected with vascular diseases.
应用
Buflomedil hydrochloride may be used as an analytical standard for the determination of buflomedil in biological matrices using high-performance liquid chromatography technique. It may also be used as an analytical reference standard for the quantification of the analyte in pharmaceutical formulations and serum samples using electroanalytical and chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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Paul P Dobesh et al.
Pharmacotherapy, 29(5), 526-553 (2009-04-29)
Peripheral artery disease, defined as atherosclerosis in the lower extremities, affects nearly 8.5 million people in the United States. Due to the frequent asymptomatic manifestation of peripheral artery disease, diagnosis may be delayed and its true incidence underestimated. However, some
Buflomedil: still too many fatal cardiac and neurological events.
Prescrire international, 20(115), 99-99 (2011-06-09)
Claudio Bucolo et al.
Pharmacoepidemiology and drug safety, 21(11), 1190-1196 (2012-08-03)
Review all the individualized cases of adverse drug reaction (ADR) potentially related to buflomedil, a vasodilator with the indication for peripheral arterial disease (PAD), marketed in Europe since the 1970s but recently suspended by the European Medicines Agency. A review
Wieslaw Tryniszewski et al.
Medical science monitor : international medical journal of experimental and clinical research, 16(12), CR622-CR627 (2010-12-02)
Most of the methods don't give the comparison between blood flow at rest and after exercise. Nuclear medicine allows for such assessment and determination of muscle perfusion indexes. The aim of the study was the comparison of the radioisotopic assessment
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